Table 2

Abnormal cardiac scans showing asymmetry between right and left sided structures

Patient	Indication	GA (weeks^+days)	Cardiac findings	Other ultrasound findings	Karyotype	Outcome
LV, left ventricle.
1	Increased NT	13⁺⁰	Asymmetry RV/LV	Increased NT of 7 mm, no other findings	Normal	Planned for serial scans; TOP at 13 weeks, postmortem severely narrowed aortic isthmus (<300 μm).
2.	Family history congenital heart disease (×2)	13⁺¹	Asymmetry RV/LV and Ao/PA, right sided heart	Diaphragmatic hernia suspected at 15 weeks; severe diaphragmatic hernia, left heart hypoplasia at 19 weeks	Normal	TOP at 21⁺³ weeks, postmortem large diaphragmatic hernia with severe lung hypoplasia, hypoplasia of the LV and severely hypoplastic aortic arch
3	Increased NT, unbalanced translocation	16⁺⁰	Asymmetry RV/LV	Progressive left ventricular outflow obstruction on subsequent scans	Unbalanced translocation (7/15)	TOP at 23⁺⁶ weeks, postmortem severe hypoplasia of LV and aortic arch
4	Increased NT	14⁺¹	Asymmetry RV/LV, right sided heart	Limb abnormality, suspected diaphragmatic hernia	Normal	TOP at 14⁺² weeks, no postmortem examination
5	Increased NT	13⁺¹	Small aortic isthmus	Increased NT of 7.9 mm; no other findings	Normal	Planned for serial scans; TOP at 13 weeks, no postmortem examination
6	Increased NT	13⁺³	Asymmetry RV/LV, distal aortic arch not seen	Cystic hygroma	45 XO	TOP at 14⁺⁰ weeks, postmortem severely narrowed aortic arch and isthmus
7	Exomphalos	14⁺²	Asymmetry RV/LV and Ao/PA	Exomphalos	Normal	Live birth, successful repair of coarctation and exomphalos