Baseline patient and procedural characteristics according to glomerular filtration rate (GFR) on admission
| All patients (n = 1400) | Group by GFR (ml/min/1.73 m2) | p Value* | ||||
|---|---|---|---|---|---|---|
| ⩾130 (n = 106) | 90–129 (n = 548) | 60–89 (n = 570) | <60 (n = 176) | |||
| Data are expressed as mean (SD) or percentage (95% confidence interval (CI)). | ||||||
| *Comparison between groups. | ||||||
| CPR, cardiopulmonary resuscitation; Gp, glycoprotein; MI, myocardial infarction. | ||||||
| GFR (ml/min/1.73 m2) | 89 (27) | 146 (15) | 105 (10) | 77 (8) | 46 (13) | |
| Age (years) | 65 (11) | 58 (11) | 61 (11) | 67 (9) | 71 (8) | <0.001 |
| Female sex (%) | 29 (27 to 32) | 22 (14 to 30) | 28 (25 to 32) | 29 (25 to 33) | 35 (28 to 42) | 0.135 |
| Prior MI (%) | 33 (31 to 36) | 22 (14 to 30) | 28 (25 to 32) | 36 (32 to 40) | 45 (38 to 53) | <0.001 |
| Prior coronary bypass grafting (%) | 14 (12 to 16) | 13 (7 to 20) | 12 (9 to 14) | 15 (12 to 18) | 15 (10 to 21) | 0.291 |
| Prior coronary angioplasty (%) | 22 (20 to 24) | 17 (10 to 24) | 22 (19 to 26) | 24 (20 to 27) | 21 (15 to 27) | 0.471 |
| Diabetes (%) | 19 (17 to 21) | 17 (10 to 24) | 16 (13 to 20) | 18 (15 to 22) | 30 (23 to 36) | 0.001 |
| Hypercholesterolaemia (%) | 66 (63 to 68) | 64 (55 to 73) | 65 (61 to 69) | 68 (64 to 72) | 63 (55 to 70) | 0.476 |
| Hypertension (%) | 62 (60 to 65) | 55 (45 to 64) | 56 (52 to 60) | 67 (63 to 70) | 71 (64 to 78) | <0.001 |
| Smoking (%) | 23 (20 to 25) | 41 (31 to 50) | 27 (23 to 30) | 18 (15 to 21) | 14 (9 to 19) | <0.001 |
| Angina pectoris at rest >48 h (%) | 16 (14 to 18) | 11 (5 to 17) | 14 (11 to 17) | 19 (16 to 22) | 17 (11 to 23) | 0.073 |
| Angina pectoris at rest <48 h (%) | 69 (67 to 72) | 67 (58 to 76) | 70 (66 to 74) | 68 (64 to 72) | 72 (65 to 78) | 0.714 |
| Non-Q wave MI (%) | 15 (13 to 17) | 22 (14 to 30) | 16 (13 to 19) | 13 (10 to 16) | 11 (7 to 16) | 0.060 |
| Mechanical CPR (%) | 1.4 (0.8 to 2.0) | 0.9 (0 to 2.8) | 0.7 (0 to 1.4) | 1.2 (0.3 to 2.1) | 4.0 (1.1 to 6.9) | 0.013 |
| Defibrillation (only) (%) | 1.7 (1.0 to 2.4) | 1.9 (0 to 4.5) | 1.3 (0.3 to 2.2) | 1.2 (0.3 to 2.1) | 4.6 (1.4 to 7.7) | 0.020 |
| Cardiogenic shock (%) | 0.9 (0.4 to 1.4) | 0 | 0.6 (0 to 1.2) | 1.2 (0.3 to 2.1) | 1.7 (0 to 3.6) | 0.313 |
| New ST depression ⩾1 mm (%) | 10 (8 to 11) | 4 (1 to 7) | 9 (7 to 12) | 9 (7 to 11) | 15 (9 to 20) | 0.021 |
| New T wave inversion ⩾1 mm (%) | 29 (26 to 31) | 38 (28 to 47) | 31 (27 to 35) | 25 (22 to 29) | 27 (21 to 34) | 0.029 |
| Troponin T ⩾0.01 μg/l (%) | 56 (53 to 59) | 52 (42 to 62) | 55 (50 to 60) | 53 (48 to 58) | 72 (64 to 80) | 0.002 |
| White cell count (×109/l) | 8.9 (7.4) | 9.1 (2.7) | 8.7 (3.0) | 8.5 (3.7) | 10.6 (18.9) | 0.010 |
| Platelet count (×109/l) | 235 (75) | 232 (62) | 235 (66) | 234 (79) | 241 (92) | 0.661 |
| Coronary vessels with ⩾50% stenosis (%) | 0.001 | |||||
| 0 | 13 (12 to 15) | 18 (10 to 25) | 15 (12 to 18) | 12 (9 to 15) | 10 (5 to 15) | |
| 1 | 25 (23 to 27) | 31 (22 to 40) | 29 (25 to 33) | 22 (18 to 25) | 18 (12 to 24) | |
| 2 | 23 (21 to 25) | 23 (14 to 31) | 23 (19 to 27) | 24 (20 to 28) | 18 (12 to 24) | |
| 3 | 39 (36 to 41) | 29 (20 to 38) | 33 (29 to 37) | 42 (38 to 46) | 53 (45 to 61) | |
| Percutaneous coronary intervention (%) | 56 (53 to 58) | 58 (48 to 67) | 58 (54 to 62) | 55 (51 to 59) | 51 (43 to 58) | 0.372 |
| With stent (%) | 80 (77 to 83) | 83 (73 to 93) | 78 (73 to 83) | 80 (76 to 85) | 80 (71 to 89) | 0.810 |
| With Gp IIb/IIIa antagonists (%) | 12 (9 to 14) | 9 (1 to 16) | 11 (7 to 14) | 11 (7 to 15) | 21 (12 to 30) | 0.060 |
| Coronary artery bypass grafting (%) | 14 (12 to 16) | 9 (4 to 15) | 12 (10 to 15) | 15 (12 to 18) | 21 (15 to 27) | 0.016 |
| Medical treatment (%) | 30 (28 to 32) | 33 (24 to 42) | 30 (26 to 34) | 30 (26 to 34) | 28 (22 to 35) | 0.877 |