Termination criteria
| For dobutamine and exercise stress echo a β blocker may be used as antidote (for example, esmolol 0.5 mg/kg as slowly injected bolus, additional bolus of 0.2 mg/kg as needed). Aminophylline (240 mg intravenously) should be available for immediate use in case of an adverse dipyridamole related event. |
| Submaximal heart rate reached [(220−age)×0.85] for dobutamine stress |
| Blood pressure decrease >20 mm Hg below baseline systolic blood pressure or decrease >20 mm Hg from a previous level |
| Blood pressure increase >240/120 mm Hg |
| Intractable symptoms |
| Complex cardiac arrhythmias |
| New or worsening wall motion/thickening abnormalities in at least two adjacent LV segments |
| New or worsening wall motion/thickening abnormalities associated with ventricular dilation |
| Development of global reduction of systolic function. |