Prevalence of aortic sclerosis based on echocardiographic findings in various study groups
| Author | Sample size | Population studied | Age (years) | Prevalence of aortic sclerosis | Relative risk of sclerosis/event |
|---|---|---|---|---|---|
| ARIC, atherosclerosis risk in communities; LIFE, losartan intervention for endpoint reduction in hypertension; LVH, left ventricular hypertrophy; MI, myocardial infarction; ND, not determined. | |||||
| Otto1 | 5621 | Population study, cardiovascular health study | >65, mean 75 (6) | 29% | 1.66/death |
| Aronow2 | 2358 | Population study | Mean 82 | 42% | 1.76/new coronary event |
| Taylor4 | 2279 | Population study, ARIC (African American) substudy | 65–74 | 18.6% | 3.8/MI or fatal coronary disease |
| Olsen5, 6 | 960 | Hypertension with ECG LVH, LIFE substudy | Mean 66 | 40.4% | 2.0/composite cardiac end point |
| Chandra3 | 425 | Admissions with chest pain | Mean 68 | 50% | 2.4/cardiovascular event |
| Agmon7 | 381 | Population study | Mean 67, range 51–101 | 36.7% | ND |
| Yamaura8 | 252 | Healthy subjects | 25–65 | 11% | ND |
| Poggianti9 | 102 | Suspected coronary disease awaiting stress echocardiography | 63.5 (9.7) | 34% | ND |