Preoperative characteristics of the patient population
Characteristic | Total (n = 155) | ΔEF >10 EFU (n = 55) | ΔEF ⩽10 EFU (n = 68) |
---|---|---|---|
Data are number (%) of patients or mean (SD). | |||
CAS, coronary artery stenosis; ΔEF, change in left ventricular ejection fraction; EFU, ejection fraction units; LV, left ventricular; NYHA, New York Heart Association; PAP, pulmonary artery pressure; PCWP, pulmonary capillary wedge pressure; RV, right ventricular. | |||
Age (years) | 72 (9) | 72 (9) | 71 (9) |
Range | 43–88 | 43–86 | 47–88 |
Age >75 years | 56 (36%) | 22 (40%) | 21 (31%) |
Men/women | 110/45 | 36/19 | 52/16 |
Symptoms | |||
Angina pectoris | 38 (25%) | 11 (20%) | 18 (26%) |
Syncope | 15 (10%) | 6 (11%) | 5 (7%) |
NYHA functional class III/IV | 138 (89%) | 51 (93%) | 60 (88%) |
LV decompensation | 70 (45%) | 26 (47%) | 28 (41%) |
LV and RV decompensation | 60 (39%) | 23 (42%) | 25 (37%) |
Median duration of symptoms (months) | 12 | 11 | 13 |
ECG | |||
Atrial fibrillation | 26 (17%) | 11 (20%) | 11 (16%) |
Left bundle branch block | 37 (24%) | 7 (13%) | 20 (29%) |
LV hypertrophy | 131 (85%) | 52 (95%) | 54 (79%) |
Cardiothoracic ratio | 0.56 (0.06) | 0.55 (0.05) | 0.56 (0.05) |
Range | 0.45–0.82 | 0.49–0.70 | 0.48–0.70 |
Echocardiogram | |||
Aortic valve area (cm2) (n = 147) | 0.6 (0.15) | 0.6 (0.25) | 0.6 (0.14) |
Range | 0.25–1.0 | 0.25–1.0 | 0.25–1.0 |
Transvalvar gradient (mm Hg) | 43 (13) | 45 (13) | 42 (11) |
Range | 13–83 | 27–83 | 18–62 |
Transvalvar gradient ⩽30 mm Hg | 17 (11%) | 5 (9%) | 9 (13%) |
Grade I or II mitral regurgitation | 108 (70%) | 44 (80%) | 46 (67%) |
LV ejection fraction (%) | 25 (5) | 25 (10) | 26 (5) |
Range | 10–30 | 10–30 | 10–30 |
Haemodynamic measurements | |||
Systolic PAP (mm Hg) (n = 87) | 52 (20) | 54 (21) | 55 (17) |
PCWP (mm Hg) (n = 64) | 21 (10) | 21 (2) | 21 (10) |
Cardiac index (ml/min/m2) (n = 59) | 2.1 (0.5) | 2.1 (0.9) | 2.2 (0.5) |
Coronary artery status | |||
Abnormal coronary angiography | 58 (41%) | 25 (45%) | 25 (37%) |
⩾70% CAS (other than left main) | 38 (27%) | 14 (25%) | 17 (25%) |
⩾50% left main CAS | 5 (3%) | 1 (2%) | 4 (6%) |
History of myocardial infarction | 16 (10%) | 4 (7%) | 8 (12%) |
Non-elective operation | 40 (26%) | 14 (25%) | 15 (22%) |
Elective operation | 115 (74%) | 41 (75%) | 53 (78%) |