Clinical outcomes in patients with ACS stratified by fasting glucose concentrations
| Fasting glucose <100 mg/dl or 5.6 mmol/l | Fasting glucose 100–126 mg/dl, or 5.6–7.0 mmol/l | Fasting glucose 110–126 mg/dl, or 6.1–7.0 mmol/l | Diabetic patients | p Value | |
|---|---|---|---|---|---|
| n = 579 | n = 407 | n = 192 | n = 777 | ||
| *MACE includes death, reinfarction, stroke, cardiogenic shock, pulmonary oedema, cardiac arrest, and atrial dysrythmia; †odds ratios and 95% confidence intervals; ‡the c index for the model was 0.726, suggesting good model discrimination, and the Hosmer-Lemeshow test statistic was 0.45, suggesting adequate model calibration and goodness of fit; p values are for comparison across all four groups. | |||||
| Death | 1.04% | 1.23% | 1.56% | 6.69% | <0.001 |
| Reinfarction | 0.49% | 1.18% | 0% | 0.96% | 0.544 |
| Stroke | 0.17% | 0% | 0% | 1.16% | 0.561 |
| Cardiogenic shock | 0.52% | 1.47% | 2.60% | 7.86% | <0.001 |
| Pulmonary oedema | 2.21% | 3.53% | 3.36% | 10.8% | <0.001 |
| Cardiac arrest | 0.69% | 1.97% | 2.60% | 5.68% | <0.001 |
| Atrial fibrillation/flutter | 4.8% | 7.15 | 10.4% | 8.5% | 0.022 |
| MACE* | 6.74% | 12.04% | 15.63% | 20.21% | <0.001 |
| Multivariate risk adjusted effect of fasting blood glucose concentrations on clinical outcome†‡ | |||||
| Fasting glucose 100–126 mg/dl or 5.6–7.0 mmol/L | 1.66 (1.05 to 2.61) | p = 0.028 | |||
| Fasting glucose 110–126 mg/dl or 6.1–7.0 mmol/L | 2.10 (1.19 to 3.41) | p = 0.008 | |||
| Diabetic patients | 3.00 (2.05 to 4.39) | p<0.001 | |||