Doppler echocardiographic assessment of left ventricular geometry and function
| Sham operated | MI | ||
|---|---|---|---|
| Vehicle | Eplerenone | ||
| Values are mean (SEM). | |||
| **p<0.01 v sham; †p<0.05 v vehicle. | |||
| LVEDd, left ventricular end diastolic dimension; LVEDV, left ventricular end diastolic volume; LVEF, left ventricular ejection fraction. | |||
| Number | 8 | 9 | 9 |
| LVEDd (mm) | 6.5 (0.3) | 11.8 (0.6)** | 10.0 (0.5)**† |
| LVEDV (µl) | 281 (12) | 602 (37)** | 507 (32)**† |
| LVEF (%) | 64 (2) | 31 (2)** | 39 (2)**† |
| E:A | 1.5 (0.1) | 10.3 (1.5)** | 6.3 (0.9)**† |
| E deceleration (m/s2) | 15 (1) | 32 (3)** | 27 (1)**† |