Gene expression after myocardial infarction
| Sham operated | MI | ||
|---|---|---|---|
| Vehicle | Eplerenone | ||
| Values are mean (SEM). | |||
| *p<0.05 v sham; **p<0.01 v sham; †p<0.05 v vehicle; ††p<0.01 v vehicle. | |||
| ANP, atrial natriuretic peptide; BNP, brain natriuretic peptide; MCP-1, monocyte chemoattractant protein 1; PAI-1, plasminogen activator inhibitor 1. | |||
| ANP | 1.00 (0.07) | 4.96 (0.41)** | 3.88 (0.29)**† |
| BNP | 1.06 (0.07) | 7.92 (0.6)** | 6.50 (0.29)**† |
| Collagen I | 1.00 (0.06) | 10.95 (1.16)** | 7.31 (0.76)**†† |
| Collagen III | 1.00 (0.06) | 8.49 (0.71)** | 5.73 (0.25)**†† |
| PAI-1 | 1.00 (0.04) | 2.48 (0.13)** | 1.57 (0.21)**† |
| MCP-1 | 1.00 (0.05) | 3.36 (0.16)** | 1.80 (0.12)**† |