Table 2

Logistic regression models evaluating the relation between post-AF clinical outcomes and anticoagulation control

Variable	All cause mortality		Bleeding events		Thromboembolic events		Ischaemic strokes
Variable	OR(75% CI)	p Value	OR(75% CI)	p Value	OR(75% CI)	p Value	OR(75% CI)	p Value
*Significant at the 5% level; †0.1 unit change in the actual INR value; ‡10% change in specified range.
CI, confidence interval; NA, not applicable; OR, odds ratio.
Age	1.057(1.045 to 1.070)	0.000*	1.029(1.008 to 1.051)	0.017*	1.026(1.012 to 1.040)	0.000*	1.020(1.003 to 1.037)	0.001*
Sex	0.842(0.689 to 1.029)	0.158	0.593(0.394 to 0.893)	0.008*	0.976(0.754 to 1.263)	0.882	1.071(0.780 to 1.470)	0.727
Length of stay	1.015(1.009 to 1.021)	0.000*	1.007(0.996 to 1.017)	0.262	1.008(1.001 to 1.015)	0.036*	1.012(1.004 to 1.019)	0.003*
Pre-AF bleeding	NA	NA	2.571(1.186 to 5.573)	0.031*	NA	NA	NA	NA
Pre-AF thromboembolic event	NA	NA	NA	NA	1.501(1.017 to 2.214)	0.048*	NA	NA
Pre-AF stroke	NA	NA	NA	NA	NA	NA	3.397(2.063 to 5.594)	0.000*
+ Mean INR†	1.049(1.025 to 1.073)	0.000*	1.017(0.974 to 1.061)	0.460	0.955(0.924 to 0.987)	0.004*	0.942(0.904 to 0.982)	0.003*
+ SD INR†	1.087(1.064 to 1.110)	0.000*	1.040(1.010 to 1.072)	0.017*	1.004(0.980 to 1.029)	0.747	1.002(0.973 to 1.033)	0.879
+ % in target range‡	0.774(0.738 to 0.811)	0.000*	0.945(0.865 to 1.033)	0.218	0.891(0.842 to 0.942)	0.000*	0.905(0.844 to 0.970)	0.006*
+ % irregular (<2.0)‡	1.172(1.119 to 1.228)	0.000*	1.008(0.917 to 1.107)	0.876	1.148(1.088 to 1.212)	0.000*	1.146(1.074 to 1.223)	0.000*
+ % irregular (>3.0)‡	1.217(1.143 to 1.296)	0.000*	1.097(0.977 to 1.232)	0.134	0.948(0.867 to 1.036)	0.229	0.903(0.802 to 1.017)	0.079
+ % out of target range‡	1.293(1.233 to 1.355)	0.000*	1.058(0.968 to 1.156)	0.218	1.123(1.061 to 1.188)	0.000*	1.105(1.031 to 1.184)	0.006*