Table 4

 Histological and immunohistochemical findings in the aortic valve (right coronary cusp) of study subjects by age

Age group (years)
1 (20–40) (n = 15)2 (41–60) (n = 17)3 (⩾61) (n = 16)p Value*
*p value between the three age groups.
Location of aortic valve lesion
    Base350
    Middle120
    Tip310
    Diffuse1816<0.001
Internal elastic lamina
    Normal710
    Dislocated5816
    Disrupted111
    Duplicated001
    Multiple abnormalities2780.004
Cellularity
    Normal931
    Slightly increased51210
    Moderately increased024
    Strongly increased1010.002
Number of macrophages
    Normal811
    Slightly increased131
    Moderately increased012
    Strongly increased1110.028
Number of T lymphocytes
    None851
    Slightly increased202
    Moderately to strongly increased0010.051
Amount of cholesterol crystals
    None14107
    Slightly increased065
    Moderately increased112
    Strongly increased0020.007
Amount of mineralisation
    None1452
    Slightly increased146
    Moderate to strongly increased088<0.001
Location of mineralisation
    Base1116
    Middle011
    Tip000
    Diffuse0070.007