Parameter | Group 1 (n = 84) | Group 2 (n = 384) | p Value (group 1 v 2) | |
---|---|---|---|---|
*p<0.05; **p<0.001; ***p<0.0001; †p = NS; (all in comparison with baseline value in the same group). | ||||
B, before valvotomy; I, immediately after valvotomy; LA, left atrial; MVA, mitral valve area; NS, non-significant difference; PAP, pulmonary arterial pressure; PVR, pulmonary vascular resistance. | ||||
Mean mitral gradient (mm Hg) | B | 17 (4.7) | 15.4 (4.9) | 0.006 |
I | 5.2 (2.2)*** | 5.4 (2.5)*** | NS | |
MVA (cm2) | B | 0.84 (0.24) | 0.83 (0.24) | NS |
I | 2.0 (0.59)*** | 1.8 (0.52)*** | <0.001 | |
Mean LA pressure (mmHg) | B | 26 (5.3) | 24.8 (5.9) | NS |
I | 14.6 (3.6)*** | 14.8 (4.4)*** | NS | |
Systolic PAP (mm Hg) | B | 48.0 (16.2) | 48.5 (17) | NS |
I | 38.3 (14.5)*** | 39.2 (14.3)*** | NS | |
PVR (dynes/s/cm5) | B | 232 (237) | 258 (230) | NS |
I | 227 (172)† | 241 (216)* | NS | |
Cardiac index (l/min/m2) | B | 3.0 (0.74) | 2.43 (0.63) | <0.0001 |
I | 3.4 (0.97)** | 2.8 (1.3)*** | <0.0001 |