Baseline clinical characteristics of 1321 patients with non-valvar atrial fibrillation
| With clinical HF | Without clinical HF | p Value | |
|---|---|---|---|
| Parametric data are expressed as mean (1 SD) and compared by two sample t test. Dichotomous variables are expressed as absolute number (percentage) and compared by χ2. Non-parametric data are expressed as median (interquartile range) and compared by Mann Whitney U test. | |||
| BP, blood pressure; CABG, coronary artery bypass grafting; FS, fractional shortening determined on M mode echocardiography; HF, heart failure; LV, left ventricular; MI, myocardial infarction; sP-sel, soluble P-selectin; vWf, von Willebrand factor. | |||
| Number | 331 | 990 | |
| Age (years) | 70 (10) | 69 (9) | 0.3 |
| Men | 226 (68%) | 716 (72%) | 0.2 |
| Medical history | |||
| Prior cerebral ischaemia | 69 (21%) | 170 (17%) | 0.1 |
| Hypertension | 217 (66%) | 529 (53%) | <0.001 |
| Diabetes mellitus | 75 (23%) | 121 (12%) | <0.001 |
| Peripheral vascular disease | 40 (12%) | 58 (6%) | <0.001 |
| Prior MI | 89 (27%) | 72 (7%) | <0.001 |
| Angina | 74 (22%) | 102 (10%) | <0.001 |
| CABG | 62 (19%) | 98 (10%) | <0.001 |
| Drug treatment at time of blood sampling | |||
| ACE inhibitor | 218 (66%) | 197 (20%) | <0.001 |
| Loop diuretic | 233 (70%) | 96 (10%) | <0.001 |
| Warfarin | 232 (70%) | 381 (39%) | <0.001 |
| Aspirin | 159 (48%) | 636 (64%) | <0.001 |
| Smoking history (former + current) | 195 (58%) | 587 (59%) | 0.9 |
| Systolic BP (mm Hg) | 136 (20) | 137 (20) | 0.4 |
| Diastolic BP (mm Hg) | 76 (11) | 79 (10) | 0.001 |
| LV dysfunction on two dimensional echocardiography | <0.001 | ||
| Normal | 144 (44%) | 853 (86%) | |
| Mild | 59 (18%) | 98 (10%) | |
| Moderate | 58 (17%) | 33 (3%) | |
| Severe | 70 (21%) | 6 (1%) | |
| FS (%) | 28 (11) | 37 (8) | <0.001 |
| Left atrial diameter (cm) | 5.0 (0.8) | 4.6 (0.7) | <0.001 |
| Regurgitation | 251 (76%) | 598 (61%) | <0.001 |
| vWf (IU/dl) | 154 (29) | 144 (31) | <0.001 |
| sP-sel (ng/ml) | 32 (26–40) | 32 (25–41) | 0.7 |