Table 1

 Baseline clinical characteristics and procedure related variables

N-acetylcysteine (n = 77)Placebo (n = 79)p Value
Values are mean (SD) or percentage.
ACE, angiotensin converting enzyme; CrCl, estimated creatinine clearance; LVEF, left ventricular ejection fraction.
Age (years)63.8 (11.30)66.5 (11.1)0.14
Male sex (%)61.057.00.72
Body mass index (kg/m2)27.0 (4.74)28.1 (4.93)0.14
Creatinine (μmol/l)123.76 (45.08)111.38 (30.94)0.05
CrCl (ml/min)59.0 (27.4)62.9 (31.1)0.41
Blood pressure (mm Hg)
    Systolic131.8 (19.4)131.3 (23.2)0.90
    Diastolic76.7 (12.4)77.6 (11.3)0.63
Hypertension87.0%84.8%0.86
Diabetes mellitus51.9%51.9%1.00
Drugs in use
    Diuretics41.6%51.9%0.25
    Calcium channel blocker10.4%15.2%0.51
    ACE inhibitor70.1%68.4%0.94
Angiographic findings0.52
    Non-obstructive disease12.9%14.0%
    Single vessel disease21.4%31.0%
    Double vessel disease28.6%26.8%
    Triple vessel disease37.1%28.2%
LVEF (%)55.359.40.30
Cardiac angiographic procedure1.00
    Coronary angiography76.7%77.3%
    Percutaneous intervention23.3%22.7%
Contrast volume (ml)102.5 (47.3)102.8 (60.4)0.97