Population characteristics and biochemical variables in 400 Pakistani patients with and without metabolic syndrome according to NCEP-ATP III criteria
| Parameter | Metabolic syndrome (n = 127) | No metabolic syndrome (n = 273) |
|---|---|---|
| Data presented as mean (SD) or median (range). | ||
| *p = 0.02 to 0.05; **p = 0.01 to 0.001; ***p<0.001; †defining criteria. | ||
| AST, aspartate aminotransferase; NCEP-ATP III, National Cholesterol Education Program Adult Treatment Panel III. | ||
| CHD(+) | 58%*** | 46% |
| Gensini score | 18 (0–154)*** | 0 (0–224) |
| Age (years) | 51.8 (9.7)*** | 48.8 (9.5) |
| Men | 76%*** | 88% |
| Blood pressure (mm Hg)† | 142 (18)/88 (9)*** | 123 (15)/80 (9) |
| BMI (kg/m2) | 26.6 (3.7)*** | 24.8 (3.4) |
| Waist (cm)† | 93 (10)*** | 89 (9) |
| Total cholesterol (mmol/l) | 4.25 (1.06) | 4.27 (1.09) |
| Triglycerides (mmol/l)† | 1.70 (0.61–3.62)*** | 1.09 (0.08–3.98) |
| HDL (mmol/l)† | 0.74 (0.19)*** | 0.82 (0.24) |
| LDL (mmol/l) | 2.70 (0.98) | 2.88 (0.96) |
| Apolipoprotein A I (g/l) | 1.14 (0.20) | 1.14 (0.20) |
| Apolipoprotein B (g/l) | 0.95 (0.26)* | 0.90 (0.25) |
| HDL:apolipoprotein A I | 0.65 (0.14)*** | 0.72 (0.15) |
| LDL:apolipoprotein B | 2.83 (0.74)*** | 3.19 (0.63) |
| AST (IU/l) | 24 (9–109) | 22 (7–171) |
| Lp(a) lipoprotein (g/l) | 0.05 (0.02–0.45) | 0.06 (0.02–0.65) |
| C reactive protein (mg/l) | 5 (0.3–87) | 6 (0.2–176) |
| Fibrinogen (g/l) | 2.20 (0.70–20.20) | 2.10 (0.80–10.60) |
| Sialic acid (mg/l) | 83 (13)*** | 78 (15) |
| Glucose (mmol/l)† | 7.70 (2.94)*** | 5.85 (1.71) |
| Insulin (pmol/l) | 25 (2–356)*** | 2 (2–449) |
| HOMA insulin resistance | 8.3 (0.4–164)*** | 0.62 (0.4–211) |
| Creatinine clearance (ml/min) | 91 (27–257) | 82 (15–276) |
| Homocysteine (μmol/l) | 18 (7–92) | 18 (6–56) |