Results of haplo.stats analysis of the 506 patients with acute myocardial infarction and 506 controls according to the haplotypes derived from T-786C and G894T*
| Variables | Frequency† | Coefficient | OR | 95% CI | p Value |
|---|---|---|---|---|---|
| *Dependent variable: presence or absence of acute myocardial infarction; independent variables: diabetes, hypertension, alcohol consumption, smoking, body mass index (BMI), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol, total cholesterol, triglycerides, and three haplotypes. The T-G haplotype was the reference group. Variables with p>0.05 are not listed. | |||||
| †Haplotype frequency estimated by expectation-maximisation algorithm; frequencies <0.01 are not listed. | |||||
| CI, confidence interval; NA, not applicable; OR, odds ratio. | |||||
| Hypertension (yes/no) | NA | 1.33 | 3.78 | 2.78 to 5.13 | 0.000 |
| Diabetes (yes/no) | NA | 1.42 | 4.16 | 2.63 to 6.55 | 0.000 |
| Alcohol consumption (yes/no) | NA | −0.79 | 1.78 | 1.26 to 2.51 | 0.000 |
| Smoking (yes/no) | NA | 0.58 | 0.45 | 0.32 to 0.64 | 0.001 |
| BMI (kg/m2) | NA | 0.06 | 1.06 | 1.02 to 1.09 | 0.001 |
| HDL-C (mmol/l) | NA | −0.30 | 0.74 | 0.68 to 0.81 | 0.000 |
| T-T (−786T, +894T) | 0.102 | −0.36 | 0.70 | 0.49 to 0.99 | 0.025 |
| T-G (−786T, +894G) | 0.801 | NA | 1.0 | NA | NA |