CHD event (n = 3582 women; n = 198 events) | |
Age (per 5 years) | 1.24 (1.08 to 1.42) | 1.24 (1.08 to 1.42) |
Systolic blood pressure (per 10 mm Hg) | 1.06 (0.99 to 1.13) | 1.05 (0.99 to 1.13) |
Total:HDL cholesterol ratio (log) | 2.26 (1.42 to 3.60) | 2.10 (1.31 to 3.37) |
Current smoker | 2.35 (1.68 to 3.30) | 2.26 (1.60 to 3.19) |
Left ventricular hypertrophy | 1.27 (0.84 to 1.93) | 1.24 (0.82 to 1.89) |
Diabetes | 0.90 (0.46 to 1.77) | 0.87 (0.44 to 1.71) |
C-reactive protein (log) | | 1.09 (0.94 to 1.27) |
Fibrinogen | | 1.04 (0.82 to 1.31) |
AUROC using rank | 0.64 (0.60 to 0.69) | 0.64 (0.60 to 0.69) |
P value for difference in AUROCs = 0.76 | | |
Sensitivity/specificity | | |
30% CHD risk threshold | 5%/99% | 6%/99% |
15% CHD risk threshold | 30%/85% | 31%/86% |
CVD event (n = 3511 women; n = 240 events) | |
Age (per 5 years) | 1.28 (1.13 to 1.45) | 1.28 (1.13 to 1.45) |
Systolic blood pressure (per 10 mm Hg) | 1.04 (0.98 to 1.11) | 1.04 (0.98 to 1.10) |
Total:HDL cholesterol ratio (log) | 2.20 (1.42 to 3.43) | 2.04 (1.29 to 3.21) |
Current smoker | 2.65 (1.96 to 3.59) | 2.55 (1.87 to 3.46) |
Left ventricular hypertrophy | 1.35 (0.92 to 1.97) | 1.32 (0.90 to 1.93) |
Diabetes | 1.06 (0.59 to 1.90) | 1.02 (0.56 to 1.83) |
C-reactive protein (log) | | 1.11 (0.96 to 1.27) |
Fibrinogen | | 1.03 (0.83 to 1.28) |
AUROC using rank | 0.65 (0.62 to 0.69) | 0.66 (0.62 to 0.69) |
P value for difference in AUROCs = 0.63 | | |
Sensitivity/specificity | | |
30% CVD risk threshold | 12%/97% | 13%/97% |
15% CVD risk threshold | 46%/75% | 46%/74% |