Baseline characteristics
| Grade 2 (n = 959) | Grade 3 (n = 360) | p Value | |
|---|---|---|---|
| Data are mean (SD) or number (%). | |||
| Age (years) | 61.9 (12.6) | 63.5 (12.3) | 0.04 |
| Men | 72.4% | 73.9% | 0.69 |
| Hypertension | 20.2% | 18.4% | 0.45 |
| Diabetes mellitus | 6.6% | 7.0% | 0.80 |
| Family history of heart disease | 37.6% | 32.7% | 0.35 |
| Prior myocardial infarction | 11.7% | 9.7% | 0.31 |
| Prior angioplasty | 4.1% | 4.5% | 0.83 |
| Prior angina | 28.7% | 22.8% | 0.03 |
| Prior stroke | 2.8% | 3.6% | 0.46 |
| Hyperlipidaemia | 6.5% | 5.3% | 0.42 |
| Current smoking | 57.7% | 64.6% | 0.03 |
| Heart rate (beats/min) | 73.2 (17.4) | 75.8 (18.4) | 0.02 |
| Systolic blood pressure (mm Hg) | 135.2 | 135.4 | 0.91 |
| Killip class ⩾II | 7.7% | 8.6% | 0.59 |
| Sum ST increase at baseline (mm) | 10.2 (5.4) | 16.9 (9.3) | <0.001 |
| Anterior infarct location, V1–V4 | 53.9% | 42.5% | <0.001 |
| Time from symptom onset to treatment (h:min) | 3:43 (2:22) | 3:43 (2:19) | 0.98 |
| Randomly assigned to fibrinolysis | 48.9% | 49.2% | 0.93 |