Between-group and within-group comparisons between patients with coronary heart disease of hospital-based and home-based cardiac rehabilitation with regard to haemostatic indices and endothelial function at baseline and after completion of a cardiac rehabilitation programme
| Hospital (n = 40) | Home (n = 41) | IntergroupBaseline* | HospitalBaseline−After† | HomeBaseline−After† | Group×Rehab effects‡ | ||
|---|---|---|---|---|---|---|---|
| p Value | p Value | p Value | F1,79 | p Value | |||
| FMD, flow-mediated dilatation; NMD, nitroglycerine-mediated dilatation; PV, plasma viscosity; sP-sel, soluble P-selectin; vWf, von Willebrand factor. | |||||||
| *Unpaired Student’s t or Mann–Whitney U tests; †paired Student’s t or Wilcoxon signed ranks tests; ‡two-way analysis of variance with repeated measures of the rehabilitation effect. Group×rehabilitation indicates group-by-rehabilitation interactions. | |||||||
| vWfbaseline (IU/dl) | 201 (61) | 182 (56) | 0.15 | ||||
| vWfafter | 173 (52) | 168 (51) | <0.001 | 0.001 | 1.77 | 0.19 | |
| Fibrinogenbaseline (g/l) | 3.28 (0.7) | 3.21 (0.9) | 0.74 | ||||
| Fibrinogenafter | 2.94 (0.8) | 2.80 (0.6) | <0.001 | 0.003 | 0.42 | 0.52 | |
| D-dimerbaseline (mg/l) | 0.28 (0.22–0.45) | 0.26 (0.21–0.43) | 0.48 | ||||
| D-dimerafter | 0.20 (0.12–0.28) | 0.20 (0.10–0.30) | <0.001 | <0.001 | 0.05 | 0.83 | |
| sP-selbaseline (ng/ml) | 82 (72–92) | 80 (75–95) | 0.87 | ||||
| sP-selafter | 79 (68–94) | 81 (71–89) | 0.21 | 0.27 | 0.002 | 0.96 | |
| PVbaseline (mPas) | 1.71 (0.14) | 1.71 (0.15) | 0.86 | ||||
| PVafter | 1.59 (0.13) | 1.65 (0.13) | <0.001 | 0.018 | 1.1 | 0.29 | |
| FMDbaseline (%) | 4.45 (1.70–6.69) | 4.14 (1.22–6.17) | 0.49 | ||||
| FMDafter | 7.50 (4.86–11.7) | 6.80 (1.75–11.3) | 0.021 | 0.006 | 0.59 | 0.44 | |
| NMDbaseline (%) | 14.1 (11.3–18.1) | 13.2 (9.41–16.4) | 0.27 | ||||
| NMDafter | 14.3 (11.2–20.0) | 13.2 (8.83–16.5) | 0.23 | 0.52 | 2.12 | 0.15 | |