Baseline characteristics of all patients according to therapeutic strategy
| Conservative treatment | Aortic valve replacement | p Value | |
|---|---|---|---|
| Values are expressed as number (%), mean (SD) or median (interquartile range). | |||
| LVMI, left ventricular mass index; NT-proBNP, N-terminal pro-B-type natriuretic peptide; NYHA, New York Heart Association. | |||
| Number | 57 | 102 | |
| Women | 29 (51%) | 50 (50%) | 0.822 |
| Age (years) | 69 (13) | 69 (10) | 0.971 |
| NYHA class | |||
| I | 22 | 12 | |
| II | 26 | 34 | <0.001 |
| III | 7 | 41 | |
| IV | 2 | 15 | |
| Atrial fibrillation | 6 (11%) | 15 (15%) | 0.455 |
| Coronary artery disease | 19 (33%) | 30 (29%) | 0.608 |
| Creatinine (μmol/l) | 84 (17) | 80 (19) | 0.265 |
| Body mass index (kg/m2) | 28.4 (3.2) | 27.3 (3.6) | 0.073 |
| Ejection fraction (%) | 59 (4) | 56 (9) | 0.022 |
| LVMI (g/m2) | 118 (38) | 140 (37) | 0.002 |
| Mean pressure gradient (mm Hg) | 32 (21) | 60 (17) | <0.001 |
| Aortic valve area (cm2) | 0.96 (0.33) | 0.69 (0.17) | <0.001 |
| NT-proBNP (pg/ml) | |||
| Baseline | 423 (163–1145) | 832 (364–2752) | 0.001 |
| (n = 57) | (n = 102) | ||
| First follow up | 456 (166–1664) | 501 (229–892) | 0.940 |
| (n = 39) | (n = 70) | ||
| Second follow up | 498 (165–1918) | 493 (225–996) | 0.842 |
| (n = 40) | (n = 83) | ||