Prevalence of congenital heart disease in survivors after twin to twin transfusion syndrome in the study cohort compared with the prevalence at birth reported by the Baltimore-Washington infant study (WIS)28 and Wren et al29
| Postnatal examination | All (n = 89) | Recipients (n = 51) | Donors (n = 38) | Prevalence per 100 live births | |
|---|---|---|---|---|---|
| WIS28 | Wren29 | ||||
| ASD, atrial septal defect; CI, confidence interval; HT, hypertension. | |||||
| Normal | 78 (87.6%) | 44 (86.3%) | 34 (89.5%) | ||
| Acquired pulmonary HT | 1 | 0 | 1 | ||
| Congenital heart disease | 10 (11.2%) | 7 (13.7%) | 3 (7.89%) | 0.49 | 0.559 |
| 95% CI | 5.52 to 19.7 | 5.70 to 26.2 | 1.66 to 9.25 | ||
| Pulmonary stenosis | 4 (4.49%) | 4 (7.84%) | 0 (0) | 0.038 | 0.033 |
| 95% CI | 1.24 to 11.1 | 2.18 to 18.9 | 0 to 9.25 | ||
| ASD (all sizes) | 5 (5.62%) | 2 (3.92%) | 3 (7.89%) | ||
| 95% CI | 1.86 to 12.6 | 0.48 to 13.5 | 0.48 to 13.5 | ||
| Medium sized ASD | 2 (2.25%) | 1 (1.96%) | 1 (2.63%) | 0.032 | 0.023 |
| 95% CI | 0.27 to 7.88 | 0.05 to 10.4 | 0.07 to 13.8 | ||
| Ventricular septal defect | 1 (1.12%) | 1 (1.96%) | 0 (0) | 0.146 | 0.188 |
| 95% CI | 0.03 to 6.10 | 0.05 to 10.4 | 0.0 to 9.25 | ||