Baseline patient characteristics
| Valsartan (n = 25) | Enalapril (n = 25) | p Value | |
|---|---|---|---|
| Values are mean (SD) or number (%). | |||
| BNP, brain natriuretic peptide; CHF, congestive heart failure; DBP, diastolic blood pressure; DCM, dilated cardiomyopathy; H/M, heart to mediastinum count; LVEDV, left ventricular end diastolic volume; LVEF, left ventricular ejection fraction; 123I-MIBG, iodine-123 labelled meta-iodobenzylguanidine; NS, not significant; NYHA, New York Heart Association; OMI, old myocardial infarction; SBP, systolic blood pressure; TDS, total defect score; WR, washout rate. | |||
| Age (years) | 67 (10) | 68 (9) | NS |
| Men/women | 16/9 | 15/10 | NS |
| Height (cm) | 160 (9) | 162 (10) | NS |
| Weight (kg) | 58 (8) | 59 (9) | NS |
| SBP (mm Hg) | 132 (16) | 131 (14) | NS |
| DBP (mm Hg) | 74 (8) | 72 (8) | NS |
| NYHA functional class | |||
| II/III | 6/19 | 6/19 | NS |
| Cause of CHF | |||
| DCM | 12 (48%) | 13 (52%) | NS |
| OMI | 8 (32%) | 9 (36%) | NS |
| Valve disease | 5 (20%) | 3 (12%) | NS |
| 123I-MIBG | |||
| TDS | 43 (8) | 43 (9) | NS |
| H/M ratio | 1.70 (0.17) | 1.68 (0.36) | NS |
| WR | 46 (11) | 47 (8) | NS |
| Echocardiography | |||
| LVEDV (ml) | 172 (42) | 173 (29) | NS |
| LVEF(%) | 31 (7) | 32 (8) | NS |
| Plasma BNP (pg/ml) | 237 (180) | 235 (154) | NS |
| Medical treatment | |||
| Loop diuretic | 25 (100%) | 25 (100%) | NS |
| β Blocker | 15 (60%) | 17 (68%) | NS |
| Spironolactone | 8 (32%) | 7 (28%) | NS |
| Nitrate | 6 (24%) | 5 (20%) | NS |
| Calcium antagonist | 6 (24%) | 9 (36%) | NS |
| Digitalis | 2 (8%) | 3 (12%) | NS |