Angiographic parameters for studies with sirolimus eluting stents
| Study | Indications for PCI | Mean RVD (mm) | Mean lesion length (mm) | Target artery (%) | ACC/AHA class (%) | Multivessel disease (%) | Previous MI (%) | AP (%) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LAD | RCA | LCX | A | B1 | B2 | C | Stable | Unstable | ||||||
| ACC, American College of Cardiology; ACS, acute coronary syndrome; AHA, American Heart Association; AP, angina pectoris; LAD, left anterior descending coronary artery; LCX, left circumflex coronary artery; MI, myocardial infarction; PCI, percutaneous coronary intervention; RCA, right coronary artery; RVD, reference vessel diameter. | ||||||||||||||
| Sirolimus trials | ||||||||||||||
| SIRIUS (2003)4 | Stable or unstable AP, signs of myocardial ischaemia | 2.80 | 14.40 | 44 | 31 | 25 | 8 | 36 | 33 | 23 | 42 | 31 | 58 | 53 |
| E-SIRIUS (2003)1 | Stable or unstable AP, silent ischaemia | 2.55 | 15.00 | 56 | 21 | 23 | NA | NA | NA | NA | 36 | 42 | NA | 33 |
| C-SIRIUS (2004)3 | Stable or unstable AP, silent ischaemia | 2.63 | 13.60 | 36 | 41 | 23 | NA | NA | 59 | 40 | 42 | 12 | 51 | |
| DIABETES (2005)30 | Symptoms or objective evidence of ischaemia | 2.34 | 15.00 | 41 | 37 | 22 | NA | NA | 80 | 65 | 37 | NA | NA | |
| RAVEL (2002)2 | Stable or unstable AP, silent ischaemia | 2.62 | 9.58 | 50 | 27 | 23 | 6 | 37 | 57 | 0 | NA | 36 | 39 | 50 |
| SES-SMART (2004)8 | ACS, stable AP, silent myocardial ischaemia as shown by exercise stress test | 2.20 | 11.84 | 28 | 16 | 30 | 25 | 47 | 24 | 4 | 65 | NA | NA | NA |
| Paclitaxel trials | ||||||||||||||
| TAXUS I (2003)5 | Stable or unstable AP or silent ischaemia | 2.97 | 11.30 | 40 | 30 | 30 | 23 | 41 | 36 | 0 | NA | 28 | NA | NA |
| TAXUS II (2003)6, 32, 33 | Stable or unstable AP or silent ischaemia | 2.75 | 10.48 | 45 | 36 | 19 | NA | NA | NA | NA | NA | 40 | 60 | 34 |
| TAXUS IV (2004)7, 29 | Stable or unstable angina or provokable ischaemia | 2.75 | 13.40 | 41 | 31 | 28 | NA | NA | NA | NA | NA | 30 | NA | 34 |
| TAXUS VI (2005)31 | Stable or unstable AP or silent ischaemia | 2.78 | 20.62 | NA | NA | 28 | 56 | NA | NA | NA | NA | |||