Baseline clinical characteristics of the study population
| Data are mean (SD) or number (%). | |
| ABPR, abnormal blood pressure response during upright exercise; ASH, asymmetrical septal hypertrophy; HCM, hypertrophic cardiomyopathy; LVOTG, left ventricular outflow tract gradient (⩾30 mm Hg); LVWT, left ventricular wall thickness; NSVT, non-sustained ventricular tachycardia on Holter monitoring; NYHA, New York Heart Association dyspnoea class; SCD, sudden cardiac death; VO2, oxygen consumption during exercise. | |
| Number | 956 |
| Age (years) | 42 (15) |
| Age at diagnosis (years) | 36 (16) |
| Men | 572 (59.8%) |
| Follow up (months) | 69 (45) |
| Family history of HCM | 487 (50.9%) |
| Family history of SCD | 297 (31.1%) |
| Ventricular fibrillation | 18 (1.9%) |
| NYHA class | |
| I | 598 (62.6%) |
| II | 326 (34.5%) |
| III–IV | 32 (3.4%) |
| Exertional chest pain | 268 (28.0%) |
| Palpitation | 251 (26.3%) |
| Syncope | 158 (16.5%) |
| ABPR | 260 (33.1%) |
| % Predicted peak VO2 | 71.5 (20.9) |
| NSVT | 175 (20.3%) |
| Maximum LVWT (mm) | 20.4 (6.2) |
| Pattern | |
| ASH | 615 (66.3%) |
| Concentric | 260 (28.0%) |
| Apical | 43 (4.6%) |
| Eccentric | 5 (0.5%) |
| Other | 5 (0.5%) |
| LVOTG | 249 (26.7%) |
| Fractional shortening (%) | 42.6 (9.0) |
| Left atrial diameter (mm) | 43.1 (8.2) |