Table 1

 Baseline characteristics of participants with calcific aortic stenosis in the treatment groups

CharacteristicAtorvastatin (n = 39)Placebo (n = 49)
Continuous variables stated as mean (SD) or median (interquartile range).
ACE, angiotensin-converting enzyme; AU, arbitrary unit; HDL, high density lipoprotein; LDL, low density lipoprotein.
Age (years)70 (8)70 (9)
Men74%78%
Body mass index (kg/m2)29 (5)28 (5)
Cardiovascular risk factors
    Hypertension2228
    Hyperlipidaemia32
    Diabetes mellitus02
    Current smoker510
Cardiovascular disease
    Coronary heart disease713
    Cerebrovascular disease57
    Peripheral vascular disease37
Drug history
    Aspirin1726
    ACE inhibitor78
    β blocker1115
    Warfarin48
Blood pressure (mm Hg)
    Systolic143 (18)140 (19)
    Diastolic82 (11)78 (11)
Lipid profile
    Total cholesterol (mmol/l)5.7 (0.9)5.5 (0.9)
    LDL cholesterol (mmol/l)3.6 (0.8)3.4 (0.7)
    HDL cholesterol (mmol/l)1.5 (0.4)1.5 (0.4)
    Total cholesterol:HDL4.2 (1.2)4.0 (1.0)
    Triglycerides (mmol/l)1.5 (0.8)1.4 (0.7)
Coronary calcification score (AU)
    Left anterior descending artery112 (40–285)207 (76–461)
    Circumflex artery0 (0–9)0 (0–4)
    Right coronary artery0 (0–29)0 (0–0)
    Total coronary score195 (57–448)235 (83–526)
    Log total coronary score (log AU)2.16 (0.68)2.30 (0.65)