Baseline characteristics among consecutive patients diagnosed with angina or non-cardiac chest pain, in those who did and did not subsequently experience the primary end point
| Angina group (n = 2366) | Non-cardiac group (n = 6396) | |||
|---|---|---|---|---|
| With 1 end point*, n = 405 (17%) | Without 1 end point, n = 1961 (83%) | With 1 end point*, n = 194 (3%) | Without 1 end point*, n = 6202 (97%) | |
| CABG, coronary artery bypass graft; ECG, electrocardiogram; PTCA, percutaneous transluminal coronary angioplasty. | ||||
| *1 (Primary) end point—death due to coronary heart disease or acute coronary syndrome. | ||||
| †Duration of chest pain before attendance at the clinic. | ||||
| ‡Percentage of patients not prescribed a statin but in whom a cholesterol check was recommended (data available for 7810 patients). | ||||
| §Data available for 8689 patients. | ||||
| Mean (SD) age (years) | 62 (11) | 62 (11) | 56 (11) | 51 (12) |
| Males | 240 (59%) | 1114 (57%) | 111 (57%) | 3129 (50%) |
| Ethnicity, n (%) | ||||
| White | 298 (74%) | 1512 (77%) | 97 (50%) | 3878 (63%) |
| South Asian | 90 (22%) | 371 (19%) | 84 (43%) | 1694 (27%) |
| Black | 17 (4%) | 78 (4%) | 13 (7%) | 630 (10%) |
| Risk factor, n (%) | ||||
| Current smoker | 92 (23%) | 451 (23%) | 52 (27%) | 1500 (24%) |
| Hypertension | 184 (45%) | 930 (47%) | 76 (39%) | 1855 (30%) |
| Diabetes | 78 (19%) | 315 (16%) | 41 (21%) | 484 (8%) |
| Duration of chest pain†, n (%) | ||||
| <4 weeks | 161 (40%) | 773 (39%) | 112 (58%) | 3148 (51%) |
| 1–⩽6 months | 155 (38%) | 769 (39%) | 50 (26%) | 1978 (32%) |
| >6–12 months | 34 (8%) | 132 (7%) | 7 (4%) | 320 (5%) |
| >1 year | 55 (14%) | 287 (15%) | 25 (13%) | 756 (12%) |
| Character of chest pain, n (%) | ||||
| Typical | 304 (75%) | 1390 (71%) | 17 (9%) | 291 (5%) |
| Atypical | 100 (25%) | 562 (29%) | 128 (66%) | 4289 (69%) |
| Non-specific | 1 (0.3%) | 9 (0.5%) | 49 (25%) | 1622 (26%) |
| Resting ECG, n (%) | ||||
| Normal | 222 (55%) | 1293 (66%) | 160 (82%) | 5616 (91%) |
| Abnormal | 183 (45%) | 668 (34%) | 34 (18%) | 586 (9%) |
| Exercise treadmill test, n (%) | ||||
| Positive | 152 (38%) | 714 (36%) | 2 (1%) | 23 (0.4%) |
| Non-diagnostic | 28 (7%) | 217 (11%) | 4 (2%) | 116 (2%) |
| Negative | 77 (19%) | 392 (20%) | 99 (51%) | 3257 (53%) |
| Not done, not indicated | 5 (1%) | 31 (2%) | 63 (33%) | 2218 (36%) |
| Not done, other reason | 143 (35%) | 607 (31%) | 26 (13%) | 588 (10%) |
| Mean (SD) systolic blood pressure (mm Hg) | 148 (21) | 147 (21) | 143 (23) | 138 (20) |
| Heart rate (beats/min) | 77 (13) | 76 (12) | 77 (13) | 77 (12) |
| Medication on discharge, n (%) | ||||
| Aspirin | 347 (86%) | 1650 (84%) | 32 (17%) | 608 (10%) |
| β-blockers | 212 (52%) | 1061 (54%) | 19 (10%) | 473 (8%) |
| Calcium blockers | 167 (41%) | 740 (38%) | 26 (13%) | 411 (7%) |
| Statin | 113 (28%) | 547 (28%) | 14 (7%) | 395 (6%) |
| Cholesterol measured‡ | 312 (83%) | 1476 (82%) | 121 (71%) | 3558 (65%) |
| Disposal§, n (%) | ||||
| Admitted | 0 | 0 | 1 (0.5%) | 12 (0.2%) |
| Cardiac outpatients | 217 (54%) | 1143 (59%) | 29 (15%) | 670 (11%) |
| Angiography | 115 (29%) | 453 (23%) | 0 | 2 (0.03%) |
| Discharged to primary care | 67 (17%) | 342 (18%) | 163 (85%) | 5475 (89%) |
| intervention | ||||
| Angiogram | 237 (59%) | 587 (30%) | 71 (37%) | 84 (1%) |
| PTCA | 68 (17%) | 134 (7%) | 25 (13%) | 8 (0.1%) |
| CABG | 68 (17%) | 161 (8%) | 15 (8%) | 5 (0.1%) |
| PTCA/CABG | 130 (32%) | 289 (15%) | 39 (20%) | 13 (0.2%) |