Clinical status
| | | |
Sat art O2 (%) | 81 (9) | 87 (6) | <0.001 |
HR (bpm) | 87 (14) | 81 (10) | <0.05 |
WHO functional class | 3.1 (0.7) | 2.5 (0.7) | <0.05 |
Exercise tolerance: 6MWT | | | |
Travelled distance (m) | 320 (108) | 394 (73) | <0.001 |
HR at the end (bpm) | 119 (17) | 112 (24) | NS |
Sat art O2 at the end (%) | 63 (17) | 71 (14) | <0.05 |
Borg index | 6.5 (1.3) | 5.3 (1.8) | <0.001 |
| | | |
Heart catheterisation pressure
| | | |
RA (mm Hg) | 12 (4) | 11 (3) | NS |
sPAP (mm Hg) | 106 (28) | 105 (37) | NS |
dPAP (mm Hg) | 52 (8) | 49 (16) | NS |
mPAP (mm Hg) | 73 (18) | 71 (22) | NS |
mCWP (mm Hg) | 12 (3) | 12 (4) | NS |
mSAP (mm Hg) | 84 (14) | 83 (18) | NS |
| | | |
Blood flow
| | | |
QP (l/m/m2) | 2.8 (0.9) | 4.0 (1.3) | <0.001 |
QS (l/m/m2) | 3.4 (1.1) | 4.2 (1.4) | <0.05 |
QP/QS | 0.9 (0.3) | 1.0 (0.3) | NS |
| | | |
Vascular resistances
| | | |
PVRi (WU.m2) | 22 (12) | 14 (9) | <0.001 |
SVRi (WU.m2) | 27 (10) | 23 (11) | <0.01 |
PVRi/SVRi | 0.9 (0.6) | 0.6 (0.5) | <0.05 |
| | | |
Biochemistry
| | | |
Packed cell volume (%) | 57 (7) | 55 (7) | NS |
Hb (mg/l) | 180 (40) | 170 (60) | NS |
Plts (1000/μl) | 198 (75) | 179 (67) | NS |
WCC (1000/μl) | 7.4 (2.3) | 7.2 (2.8) | NS |
Aspartate aminotranferase (U/l) | 24 (9) | 28 (12) | NS |
Alanine aminotranferase (U/l) | 31 (21) | 31 (19) | NS |
pH | 7.37 (0.05) | 7.38 (0.07) | NS |
Pao2 (mm Hg) | 45.5 (5.2) | 50.3 (10.1) | NS |
Paco2 (mm Hg) | 39.3 (8.6) | 38.9 (7.3) | NS |