Table 1

 Clinical characteristics of the treatment groups

TMZ (n = 40)Control (n = 42)p Value
BMI, body mass index; LVEF, left ventricular ejection fraction; NS, not significant; TAC, total antioxidant capacity; TMZ, trimetazidine.
Values are represented as mean (SD).
Age (years)61 (10)60 (11)NS
Men/women25/1532/10NS
Blood pressure (mm Hg)
    Systolic146 (28)149 (26)NS
    Diastolic77 (8)79 (9)NS
Diabetes mellitus (%)2026NS
BMI26.6 (4.2)25.9 (2.7)NS
LVEF (%)48 (20)47 (18)NS
TAC (mmol/ml)2.15 (0.14)2.25 (0.14)NS
Baseline serum creatinine(mg/dl)1.31 (0.25)1.26 (0.16)NS
(mmol/l)116.4 (22.8)111.9 (14.9)NS
Baseline creatinine clearance (ml/min)54.4 (13)52.4 (11)NS