ECG | Rest | After exercise | Difference between rest and exercise | ||||||
---|---|---|---|---|---|---|---|---|---|

Aortic stenosis | Controls | p Value | Aortic stenosis | Controls | p Value | Aortic stenosis | Controls | p Value | |

*Mann–Whitney U test used where variables are not normally distributed. | |||||||||

†For post-exercise, S’ and difference between rest and exercise of S’ p values were 0.0002 and 0.0005, respectively after adjusting for age, sex, body mass index, heart rat and exercise time with analysis of covariance. After excluding the six patients with aortic stenosis taking a β-blocker, p values were 0.01 and 0.006, respectively. | |||||||||

‡RSVP could be measured after exercise in 16 patients with aortic stenosis and 14 controls. | |||||||||

Ejection fraction, % | 69 (7) | 62 (5) | 0.01† | 72 (9) | 73 (9) | 0.6* | 4 (7) | 11 (8) | 0.02 |

End systolic volume, ml | 37 (19) | 48 (14) | 0.08 | 23 (12) | 23 (13) | 0.8* | −13 (19) | −25 (10) | 0.03* |

End diastolic volume, ml | 94 (33) | 119 (33) | 0.04 | 83 (25) | 81 (23) | 1.0* | −12 (32) | −38 (24) | 0.01 |

Peak systolic mitral annularvelocity, S’, cm/s | 8.5 (1.5) | 9.1 (1.8) | 0.15 | 12.2 (3.2) | 17 (2.8) | <0.001† | 4 (3) | 7.9 (1.5) | <0.001† |

Velocity time integral of S’, cm | 1.58 (0.4) | 1.85 (0.4) | 0.04 | 1.66 (0.51) | 2.24 (0.21) | 0.0003 | 0.13 (0.38) | 0.41 (0.47) | 0.04 |

Right ventricular systolicpressure, mm Hg‡ | 21 (6) | 19 (4) | 0.3 | 47 (15) | 35 (9) | 0.03* | 26 (14) | 17 (9) | 0.05* |