Univariate and multivariate analysis of the haemodynamic variables in which variation predicts a change in the index of aortic stenosis severity
| AS severity index | Haemodynamic variable | Univariate r (p value) |
|---|---|---|
| AS, aortic stenosis; AVA, aortic valve area; BP, blood pressure; ELCo, energy loss coefficient; % LVSW loss, percentage left ventricular stroke work loss index; ΔPmean, mean transvalvular pressure gradient; Qmean, mean transvalvular flow rate; SAC, systemic arterial compliance; SVR, systemic vascular resistance. | ||
| *p<0.01 on multivariate analysis. | ||
| ΔPmean | Δ AVA | –0.42 (0.004)* |
| AVA | Δ Mean BP | –0.34 (0.026) |
| Δ Systolic BP | –0.32 (0.033) | |
| Δ SVR | –0.28 (0.061) | |
| Δ SAC | 0.38 (0.011) | |
| Δ Qmean | 0.81 (<0.001)* | |
| Resistance % LVSW loss | Δ Qmean | –0.73 (<0.001)* |
| Δ Heart rate | –0.31 (0.044) | |
| Δ Mean BP | –0.78 (<0.001) | |
| Δ Systolic BP | –0.82 (<0.001)* | |
| Δ SVR | –0.54 (<0.001) | |
| Δ SAC | 0.84 (<0.001)* | |
| ELCo | Δ Mean BP | –0.36 (0.018) |
| Δ Systolic BP | –0.32 (0.036) | |
| Δ SVR | –0.30 (0.045) | |
| Δ SAC | 0.31 (0.038) | |
| Δ Qmean | 0.71 (<0.001)* | |