| Statistics | QRISK equation | Framingham equation | ||
| In QRESEARCH validation cohort | In THIN validation cohort | In QRESEARCH validation cohort | In THIN validation cohort | |
| Women | ||||
| ROC statistic | 0.7879 (0.7842 to 0.7915) | 0.7888 (0.7858 to 0.7918) | 0.7759 (0.7723 to 0.7796) | 0.7595 (0.7564 to 0.7626) |
| D statistic | 1.535 (1.508 to 1.562) | 1.556 (1.532 to 1.580) | 1.397 (1.370 to 1.424) | 1.378 (1.354 to 1.402) |
| R2 statistic (%) | 36.01 (35.16 to 36.86) | 36.64 (35.94 to 37.34) | 31.79 (30.92 to 32.66) | 31.18 (30.45 to 31.91) |
| Brier score | 0.0370 | 0.0321 | 0.0382 | 0.0338 |
| Predicted/observed (women) | 1.00 | 0.90 | 1.19 | 1.10 |
| Men | ||||
| ROC statistic | 0.7700 (0.7667 to 0.7733) | 0.7619 (0.7592 to 0.7646) | 0.7619 (0.7586 to 0.7653) | 0.7365 (0.7336 to 0.7394) |
| D statistic | 1.425 (1.401 to 1.449) | 1.394 (1.374 to 1.414) | 1.317 (1.293 to 1.341) | 1.255 (1.235 to 1.275) |
| R2 statistic (%) | 32.64 (31.88 to 33.39) | 31.70 (31.09 to 32.31) | 29.30 (28.54 to 30.05) | 27.31 (26.69 to 27.93) |
| Brier score | 0.0504 | 0.0470 | 0.0569 | 0.055 |
| Predicted/observed (men) | 0.97 | 0.87 | 1.49 | 1.32 |
| Predicted/observed (overall) | 0.99 | 0.88 | 1.36 | 1.23 |
Results are shown as mean (95% CI) unless stated otherwise.
Note that higher values for the ROC, D and R2 indicate better discrimination. Lower values of the Brier score indicate better calibration.
ROC, receiver operator curve.