Drug | Women | Men | OR (95% CI) for men | p Value | OR (95% CI) for age* | p Value |
No HF drug | 37 (1.0) | 42 (1.0) | 1.21 (0.76 to 1.91) | 0.423 | 1.02 (1.00 to 1.05) | 0.030 |
Diuretic alone | 602 (15.8) | 441 (10.8) | 0.79 (0.69 to 0.91) | 0.001 | 1.04 (1.03 to 1.05) | <0.001 |
Diuretic | 3400 (89.1) | 3664 (89.5) | 1.08 (0.93 to 1.25) | 0.318 | 1.01 (1.00 to 1.01) | 0.049 |
ACE/AIIRA | 2538 (66.5) | 3008 (73.4) | 1.21 (1.09 to 1.33) | <0.001 | 0.97 (0.97 to 0.98) | <0.001 |
β-Blocker | 1195 (31.3) | 1537 (37.5) | 1.15 (1.04 to 1.27) | <0.001 | 0.98 (0.97 to 0.98) | <0.001 |
Aldosterone antagonist | 915 (23.4) | 1256 (30.1) | 1.25 (1.13 to 1.39) | <0.001 | 0.98 (0.97 to 0.98) | <0.001 |
Diuretic and ACE/AIIRA | 2349 (61.5) | 2793 (68.2) | 1.20 (1.09 to 1.32) | <0.001 | 0.98 (0.97 to 0.98) | <0.001 |
All four drugs | 230 (6.0) | 438 (10.7) | 1.54 (1.30 to 1.83) | <0.001 | 0.96 (0.96 to 0.97) | <0.001 |
Death | 729 (16.0) | 683 (14.3) | 1.13 (1.00, 1.27) | 0.042 | 1.06 (1.05, 1.06) | <0.001 |
AIIRA, angiotensin II receptor antagonist, HF, heart failure.
*OR per year of increasing age.