Table 1 Joinpoint analysis: trends in age-specific coronary heart disease mortality rates in England and Wales 1984–2004 (adults aged 35+ years)

Age	Period 1		Period 2		Period 3		Period 4
Age	Years	EAPC (95% CI)	Years	EAPC (95% CI)	Years	EAPC (95% CI)	Years	EAPC (95% CI)
Men
35–44	1984–91	−3.7* (−4.8 to −2.6)	1991–2000	−6.9* (−7.91 to −5.8)	2000–4	−2.4 (−5.9 to 1.4)
45–54	1984–87	−3.4* (−5.6 to −1.1)	1987–94	−9.4* (−10.2 to −8.5)	1994–99	−5.8* (−7.8 to −3.8)	1999–2004	−1.8* (−3.4 to −0.2)
55–64	1984–87	−1.5* (−2.9 to −0.01)	1987–93	−4.8* (−5.5 to −4.5)	1993–98	−6.4* (−7.8 to −5.3)	1998–2004	−9.5* (−10.2 to −8.8)
65–74	1984–93	−3.8* (−4.1 to −3.5)	1993–99	−4.8* (−5.7 to −3.9)	1999–2004	−8.3* (−9.4 to −7.2)
75+	1984–89	−4.6* (−5.8 to −3.3)	1989–94	−1.3 (−3.2 to 0.5)	1994–2004	−6.1* (−6.6 to −5.6)

Women
35–44	1984–2004	−3.2* (−3.6 to −2.9)
45–54	1984–90	−6.6* (−7.8 to −5.3)	1990–95	−8.9* (−11.6 to −6.2)	1995–2004	−3.5* (−4.5 to −2.5)
55–64	1984–90	−1.6* (−2.7 to −0.5)	1990–98	−6.6* (−7.6 to −5.6)	1998–2004	−11.3 (−12.9 to −9.6)
65–74	1984–92	−2.8* (−3.3 to −2.4)	1992–99	−4.5* (−5.2 to −3.7)	1999–2004	−8.3* (−9.5 to −7.1)
75+	1984–88	−3.5* (−5.5 to −1.4)	1988–93	0.9 (−3.1 to 1.2)	1993–2000	−4.9* (−6.1 to −3.7)	2000–4	−2.7* (−5.2 to −0.1)

EAPC, estimated annual percentage change.
*Significantly different from 0.