Characteristics | All patients(n = 88) | Major adverse outcomes(n = 18) | No major adverse outcomes(n = 70) | p Value |
Gender (M/F) | 1.2 | 0.8 | 1.3 | NS |
Diagnosis (%) | NS | |||
TOF with pulmonary stenosis | 71 | 67 | 71 | |
TOF with pulmonary atresia | 29 | 33 | 29 | |
Type of TOF repair (%) | NS | |||
RVOT patch | 74 | 72 | 74 | |
RV-pulmonary artery conduit | 26 | 28 | 26 | |
Median age at TOF repair (years) (range) | 3.0 (0–29.8) | 11.8 (0.53–21.7) | 2.1 (0.01–29.8) | <0.001 |
Era of TOF repair (%) | 0.034 | |||
Before 1970 | 15 | 33 | 10 | |
1970–9 | 39 | 39 | 39 | |
1980 or later | 46 | 28 | 51 | |
Median age at baseline evaluation (years) (range) | 24.0 (10.0–57.6) | 36.9 (13.5–55.3) | 20.9 (10.0–57.6) | 0.002 |
Median time from TOF repair to baseline evaluation (years) (range) | 20.7 (10–42.6) | 25.3 (12.9–36.4) | 19.2 (10.0–42.6) | 0.028 |
Median age at most recent follow-up (years) (range) | 28.1 (14.1–61.7) | 39.4 (16.7–57.6) | 24.9 (14.1–61.7) | 0.002 |
Median follow-up from baseline evaluation (years) (range) | 4.2 (0.17–7.3) | 4.2 (0.2–5.5) | 4.3 (0.5–7.3) | NS |
Cardiac MR variables at baseline evaluation, mean (SD) | ||||
Pulmonary regurgitation fraction (%) | 31 (19) | 31 (21) | 31 (18) | NS |
Pulmonary regurgitation volume (ml/m2) | 16 (15) | 16 (16) | 16 (14) | NS |
RV end-diastolic volume (Z) | 3.91 (3.27) | 5.34 (3.36) | 3.55 (3.17) | 0.06 |
RV end-systolic volume index (ml/m2) | 66 (33) | 85 (36) | 61 (30) | 0.017 |
RV ejection fraction (%) | 48 (12) | 38 (12) | 50 (11) | 0.001 |
RV mass index (g/m2) | 61 (25) | 66 (27) | 60 (24) | NS |
RV mass/volume | 0.54 (0.18) | 0.53 (0.18) | 0.55 (0.18) | NS |
LV end-diastolic volume (Z) | –0.04 (2.3) | –0.14 (3.27) | –0.02 (2.03) | NS |
LV end-systolic volume index (ml/m2) | 29 (13) | 36 (22) | 27 (9) | NS |
LV ejection fraction (%) | 60 (9) | 54 (10) | 61 (8) | 0.015 |
LV mass index (g/m2) | 90 (27) | 106 (39) | 86 (22) | 0.07 |
LV mass/volume | 1.33 (0.32) | 1.54 (0.42) | 1.28 (0.27) | 0.033 |
QRS duration (ms) | 158 (27) | 179 (23) | 153 (26) | <0.001 |
LV, left ventricle; MR, magnetic resonance; RV, right ventricle; RVOT, right ventricular outflow tract; TOF, tetralogy of Fallot.