Table 2 Outcome by randomised therapy in the overall population
nControlCRTHR (95% CI)p Value
404 (%)409 (%)
Death or CV hosp (main study)224 (55)159 (39)0.63 (0.51 to 0.77)<0.001
Death or HF hosp (main study)191 (47)118 (29)0.54 (0.43 to 0.68)<0.001
All-cause mortality*154 (38)101 (25)0.60 (0.47 to 0.77)<0.001
Sudden death*54 (13.4)32 (7.8)0.54 (0.35 to 0.84)0.005
By 18 months
Investigator-assigned NYHA I/II151 (37)255 (62)0.36 (0.27 to 0.48)<0.001
MLWHF Score ⩽35166 (41)213 (52)0.64 (0.48 to 0.86)0.002
CRT implanted33 (8)390 (95)N/AN/A
  • Numbers and percentages are shown for each outcome.

  • CRT, cardiac resynchronisation therapy; CV hosp, cardiovascular hospitalisation; HF hosp, heart failure hospitalisation; MLWHFQ, Minnesota living with heart failure questionnaire. N/A, analysis not appropriate.

  • *Includes data from both the main study and extension phase.