Variables | Men | Women | ||||||
All | With CAD | Unadjusted odds ratio (95% CI) | Adjusted odds ratio (95% CI) | All | With CAD | Unadjusted odds ratio (95% CI) | Adjusted odds ratio (95% CI) | |
Subjects, No (%) | 1211 | 90 (7.4) | 1011 | 63 (6.2) | ||||
Age (years), mean (SD) | 51.3 (10.2) | 56.6 (10.4) | 1.05 (1.03 to 1.06) | 1.03 (1.01 to 1.05) | 50.9 (10.3) | 56.5 (10.6) | 1.02 (1.01 to 1.03) | 1.03 (1.01 to 1.04) |
Past smoker†, No (%) | 300 (94.0) | 60.0 (20.0) | 3.13 (2.04 to 4.77) | 2.64 (1.72 to 4.06) | 15 (1.5) | 1 (1.6) | 0.91 (0.35 to 2.36) | NS§ |
Waist to hip ratio, mean (SD) | 0.94 (0.08) | 0.97 (0.07) | 1.51 (1.19 to 1.91) | NS | 0.86 (0.07) | 0.90 (0.08) | 1.87 (1.41 to 2.48) | 1.70 (1.28 to 2.26) |
Body mass index, mean (SD) | 24.2 (4.7) | 25.5 (4.8) | 1.05 (1.01 to 1.10) | NS | 26.5 (5.7) | 26.3 (4.6) | 0.99 (0.96 to 1.02) | NS |
Hypertriglyceridaemia, No (%) | 475 (39.2) | 43 (47.8) | 1.45 (0.95 to 2.23) | NS | 387 (38.2) | 29 (46.0) | 1.40 (0.77 to 2.54) | NS |
Low LDL, No (%) | 443 (36.6) | 28 (31.1) | 0.76 (0.50 to 1.17) | NS | 351 (34.7) | 18 (28.6) | 0.73 (0.50 to 1.08) | NS |
Low HDL, No (%) | 857 (70.7) | 62 (68.9) | 0.90 (0.62 to 1.31) | NS | 790 (78.1) | 51 (81.0) | 1.20 (0.66 to 2.18) | NS |
Exercise, No (%) | 385 (31.8) | 19 (21.1) | 0.55 (0.31 to 0.95) | NS | 184 (18.2) | 12 (19.1) | 1.06 (0.46 to 2.41) | NS |
Hypertension, No (%) | 351 (29.0) | 46 (51.1) | 2.79 (1.73 to 4.51) | 2.25 (1.33 to 3.80) | 467 (46.1) | 46 (73.0) | 3.38 (1.87 to 6.13) | 2.73 (1.61 to 4.64) |
Diabetes, No (%) | 207 (17.0) | 30 (33.3) | 2.66 (1.99 to 3.56) | 2.57 (1.80 to 3.68) | 227 (22.4) | 26 (41.3) | 2.61 (1.37 to 4.95) | NS |
Metabolic syndrome‡ , No (%) | 543 (44.8) | 55 (61.1) | 2.03 (1.45 to 2.85) | Not applicable | 553 (54.7) | 45 (71.4) | 2.16 (1.19 to 3.90) | Not applicable |
*CAD defined as presence of major Q waves on ECG or history of heart attack diagnosed by a doctor.
†Past smokers defined as those who smoked ⩾100 cigarettes in their lifetime.
‡Metabolic syndrome defined as the concomitant presence of at least three of the following: hypertension, high triglycerides (>1.70 mmol/l); or low HDL cholesterol (<1.04 mmol/l in men or <1.30 mmol/l in women), impaired glucose tolerance (fasting glucose ⩾6.1 mmol/l), or central obesity.
§NS, not significant in the multivariable model and therefore not retained in the final model.
HDL, high-density lipoprotein; LDL, low-density lipoprotein.