Table 3 Factors associated with definite coronary artery disease (CAD)* in men and women
VariablesMenWomen
AllWith CADUnadjusted odds ratio (95% CI)Adjusted odds ratio (95% CI)AllWith CADUnadjusted odds ratio (95% CI)Adjusted odds ratio (95% CI)
Subjects, No (%)121190 (7.4)101163 (6.2)
Age (years), mean (SD)51.3 (10.2)56.6 (10.4)1.05 (1.03 to 1.06)1.03 (1.01 to 1.05)50.9 (10.3)56.5 (10.6)1.02 (1.01 to 1.03)1.03 (1.01 to 1.04)
Past smoker†, No (%)300 (94.0)60.0 (20.0)3.13 (2.04 to 4.77)2.64 (1.72 to 4.06)15 (1.5)1 (1.6)0.91 (0.35 to 2.36)NS§
Waist to hip ratio, mean (SD)0.94 (0.08)0.97 (0.07)1.51 (1.19 to 1.91)NS0.86 (0.07)0.90 (0.08)1.87 (1.41 to 2.48)1.70 (1.28 to 2.26)
Body mass index, mean (SD)24.2 (4.7)25.5 (4.8)1.05 (1.01 to 1.10)NS26.5 (5.7)26.3 (4.6)0.99 (0.96 to 1.02)NS
Hypertriglyceridaemia, No (%)475 (39.2)43 (47.8)1.45 (0.95 to 2.23)NS387 (38.2)29 (46.0)1.40 (0.77 to 2.54)NS
Low LDL, No (%)443 (36.6)28 (31.1)0.76 (0.50 to 1.17)NS351 (34.7)18 (28.6)0.73 (0.50 to 1.08)NS
Low HDL, No (%)857 (70.7)62 (68.9)0.90 (0.62 to 1.31)NS790 (78.1)51 (81.0)1.20 (0.66 to 2.18)NS
Exercise, No (%)385 (31.8)19 (21.1)0.55 (0.31 to 0.95)NS184 (18.2)12 (19.1)1.06 (0.46 to 2.41)NS
Hypertension, No (%)351 (29.0)46 (51.1)2.79 (1.73 to 4.51)2.25 (1.33 to 3.80)467 (46.1)46 (73.0)3.38 (1.87 to 6.13)2.73 (1.61 to 4.64)
Diabetes, No (%)207 (17.0)30 (33.3)2.66 (1.99 to 3.56)2.57 (1.80 to 3.68)227 (22.4)26 (41.3)2.61 (1.37 to 4.95)NS
Metabolic syndrome‡ , No (%)543 (44.8)55 (61.1)2.03 (1.45 to 2.85)Not applicable553 (54.7)45 (71.4)2.16 (1.19 to 3.90)Not applicable
  • *CAD defined as presence of major Q waves on ECG or history of heart attack diagnosed by a doctor.

  • †Past smokers defined as those who smoked ⩾100 cigarettes in their lifetime.

  • ‡Metabolic syndrome defined as the concomitant presence of at least three of the following: hypertension, high triglycerides (>1.70 mmol/l); or low HDL cholesterol (<1.04 mmol/l in men or <1.30 mmol/l in women), impaired glucose tolerance (fasting glucose ⩾6.1 mmol/l), or central obesity.

  • §NS, not significant in the multivariable model and therefore not retained in the final model.

  • HDL, high-density lipoprotein; LDL, low-density lipoprotein.