Study (reference) | Country | Participants (n) | Mean age (years) | Men (%) | LVSD criteria | Prevalence of LVSD (%) | Prevalence of LVSD without CHF† |
EF >0.40, or equivalent | |||||||
Strong Heart study4 | USA | 3184 | 58 | 37 | EF ⩽0.54 | 14.0 | 12.5 |
HyperGEN study6 | USA | 2086 | 55 | 38 | EF ⩽0.54 | 14.0 | 12.9 |
Davies et al7 | England | 3960 | 61 | 50 | EF ⩽0.50 | 5.3 | 3.3 |
MONICA project (Augsburg)15 | Germany | 1566 | 50 | 48 | EF ⩽0.48 | 2.7 | 1.1 |
Hedberg et al16 | Sweden | 412 | 75 | 50 | WMI ⩾1.7 | 6.8 | 3.2 |
Nielsen et al17 | Denmark | 126 | 70 | 55 | WMI ⩾1.5 or FS ⩽0.26 | 2.9 | 1.0 |
Rotterdam study18 | Netherlands | 2267 | 66 | 45 | FS ⩽0.25 | 3.7 | 2.9 |
Helsinki Ageing study19 | Finland | 501 | — | 27 | FS ⩽0.25 | 10.8 | 8.6 |
EF ⩽0.40 | |||||||
Strong Heart study4 | USA | 3184 | 58 | 37 | EF ⩽0.40 | 2.9 | 2.1 |
HyperGEN study6 | USA | 2086 | 55 | 38 | EF ⩽0.40 | 4.0 | 3.4 |
Davies et al7 | England | 3960 | 61 | 50 | EF ⩽0.40 | 1.8 | 0.9 |
MONICA project (Glasgow)8 | Scotland | 1467 | 50 | 48 | EF ⩽0.35 | 7.7 | 5.9 |
MONICA project (Glasgow)8 | Scotland | 1467 | 50 | 48 | EF ⩽0.30 | 2.9 | 1.4 |
Qualitatively “reduced” EF | |||||||
Cardiovascular Health study20 | USA | 5532 | 73 | 42 | Qualitative | 3.5 | 2.5 |
Morgan et al21 | England | 817 | 76 | 46 | Qualitative | 7.5 | 3.9 |
CHF, congestive heart failure; EF, ejection fraction; FS, fractional shortening; HyperGEN, Hypertension Genetic Epidemiology Network; LVSD, left ventricular systolic dysfunction; MONICA, Monitoring Trends and Determinants in Cardiovascular Disease; WMI, wall-motion index.