Table 2 Patient characteristics by their first C-reactive protein (CRP) observation
CharacteristicsAll subjectsNormal CRP ⩽3 mg/lElevated CRP 4–10 mg/lAcutely high CRP >10 mg/lp Value
Number of subjects (n)581182815313452
Age (years), mean (SD)61.3 (20.29)56.2 (21.8)59.9 (19.8)63.1 (19.9)ANOVA <0.001
Female (%)56.254.460.854.7χ2<0.001
Total cholesterol (mmol/l), mean (SD)4.7 (1.4)4.7 (1.2)4.8 (1.5)4.7 (1.3)ANOVA 0.186
LDL (mmol/l), mean (SD)2.9 (1.0)3.1 (0.8)2.9 (1.0)2.8 (1.1)ANOVA 0.291
With prior diabetes (%)10.58.98.811.6χ2 0.010
With prior vascular disease (%)37.429.134.440.6LLA <0.001
With prior cancer (%)8.76.37.29.9LLA 0.001
Dead within 3 years of CRP observation period (%)13.29.112.120.0LLA <0.001
Experiencing acute ischaemic event within 3 years of CRP observation (%)2.71.73.32.7LLA 0.339
  • ANOVA, one-way analysis of variance; χ2, chi-square test; LDL, low-density lipoprotein; LLA, linear-by-linear association.