| Neurohormones | Day | ||||||
| 1 | 2 | 3 | 4 | 5 | 30 | 90 | |
| PRA (nmol/l/h) | |||||||
| Placebo | 1.65 (0.66) | 2.58 (0.77) | 4.11 (1.42) | 4.77 (1.75) | 7.78 (1.95) | 2.48 (0.70) | 3.13 (0.95) |
| BNP | 3.11 (1.10) | 6.43 (1.50) | 4.20 (1.08) | 5.03 (0.97) | 3.24 (0.90) | 2.30 (0.61) | 2.52 (1.00) |
| Aldosterone (pmol/l) | |||||||
| Placebo | 156.75 (26.16) | 119.08 (14.89) | 175.0 (57.18) | 131.82 (31.63) | 140.36 (26.00) | 121.18 (18.70) | 117.18 (17.58) |
| BNP | 157.00 (27.48) | 152.36 (38.76) | 153.57 (46.04) | 130.50 (34.73) | 89.85 (12.28) | 142.77 (29.77) | 123.42 (16.91) |
| Norepinephrine (pmol/l) | |||||||
| Placebo | 4137.58 (1035.41) | 3189.17 (398.60) | 3110.83 (477.87) | 2714.55 (288.02) | 3661.82 (543.79) | 2688.18 (371.19) | 3131.67 (373.95) |
| BNP | 4140.00 (524.71) | 4117.14 (706.38) | 4881.43 (681.53) | 3525.71 (365.74) | 3476.92 (267.86) | 4330.71 (840.63) | 3399.29 (410.66) |
| ADM (pmol/l) | |||||||
| Placebo | 12.28 (1.06) | 12.65 (1.56) | 9.42 (0.88) | 9.84 (1.08) | 10.44 (1.14) | 9.20 (0.83) | 8.74 (0.61) |
| BNP | 12.28 (1.34) | 12.22 (0.92) | 11.56 (1.36) | 9.60 (0.94) | 9.05 (0.92) | 7.97 (0.46) | 7.90 (0.59) |
| Endothelin (pmol/l) | |||||||
| Placebo | 1.72 (0.16) | 1.68 (0.13) | 1.74 (0.31) | 1.56 (0.23) | 1.48 (0.13) | 1.24 (0.08) | 1.32 (0.10) |
| BNP | 1.97 (0.16) | 1.85 (0.15) | 1.83 (0.15) | 1.70 (0.13) | 1.69 (0.15) | 1.63 (0.14) | 1.72 (0.23) |
Results are shown as mean (SEM).
ADM, adrenomedullin; BNP, B-type natriuretic peptide; PRA, plasma renin activity.