Table 2 Odds ratios for patient outcomes according to IL-10 level at admission
IL-10 quartileUnivariateModel 1Model 2
Percentage (no. of events/total no.)OR (95% CI)p ValueAdj OR (95% CI)p ValueAdj OR (95% CI)p Value
Death11.6% (13/805)ReferenceReferenceReference
23.4% (27/797)1.9 (0.9 to 3.8)0.0801.6 (0.8 to 3.2)0.2341.4 (0.7 to 3.0)0.35
34.7% (37/789)2.7 (1.4 to 5.3)0.0041.8 (0.9 to 3.6)0.1051.5 (0.7 to 3.0)0.30
46.1% (48/788)3.4 (1.8 to 6.5)<0.0012.6 (1.3 to 5.1)0.0071.7 (0.8 to 3.6)0.13
MI18.3% (67/805)ReferenceReferenceReference
212.3% (98/797)1.5 (1.1 to 2.2)0.0151.3 (0.9 to 1.9)0.1341.3 (0.9 to 1.9)0.134
313.3% (105/789)1.7 (1.2 to 2.4)0.0021.3 (0.9 to 1.9)0.1071.4 (1.0 to 1.9)0.066
411.7% (92/788)1.5 (1.0 to 2.1)0.0251.1 (0.8 to 1.6)0.4761.3 (0.9 to 1.9)0.182
19.4% (76/805)ReferenceReferenceReference
Composite of death/MI214.3% (114/797)1.5 (1.1 to 2.1)0.0111.3 (0.9 to 1.8)0.1301.3 (0.9 to 1.8)0.172
316.0% (126/789)1.8 (1.3 to 2.5)<0.0011.4 (1.0 to 1.9)0.071.3 (1.0 to 1.9)0.095
415.6% (123/788)1.7 (1.2 to 2.3)0.0021.3 (0.9 to 1.8)0.1381.3 (0.9 to 1.8)0.190
  • Model 1 adjusted for age, sex, BMI, previous MI, hypertension, diabetes, ST-depression at entry, dalteparin/placebo, TnT>0.03 μg/l, cholesterol >5.5 mM, smoking, creatinine clearance, NT-pro-BNP, use of aspirin, ACE-inhibitor, β-blocker and statins. Model 2 included also CRP and IL-6>5 ng/l.