| Characteristics | All patients | Patients with STEMI | Patients with NSTE-ACS | |||
| No AF | AF | No AF | AF | No AF | AF | |
| Patients (n). | 111 529 | 9037 | 77 440 | 6721 | 34 089 | 2316 |
| Age (years), median (25th, 75th) | 62.2 (53.0, 70.7) | 70.0 (63.0, 76.0) | 61.0 (51.7, 69.7) | 69.4 (62.0, 75.9) | 65.0 (56.0, 72.2) | 71.0 (65.0, 77.0) |
| Female | 27.4 | 31.8 | 24.5 | 30.9 | 34.2† | 34.2† |
| Race | ||||||
| White | 90.9 | 94.9 | 91.8 | 95.5 | 89.0 | 93.2 |
| Black | 3.1 | 1.5 | 2.4 | 1.2 | 4.6 | 2.5 |
| Other | 6.0 | 3.6 | 5.8 | 3.3 | 6.4 | 4.4 |
| Smoking status | ||||||
| Never | 31.6 | 37.9 | 28.7 | 36.2 | 38.3 | 42.7 |
| Previous | 29.2 | 35.2 | 27.0 | 33.2 | 34.2 | 40.9 |
| Current | 39.1 | 26.9 | 44.3 | 30.6 | 27.5 | 16.4 |
| Killip class | ||||||
| I | 87.9 | 76.4 | 87.3 | 75.6 | 89.1 | 78.9 |
| II | 10.5 | 19.4 | 11.0 | 19.8 | 9.2 | 17.9 |
| III | 1.2 | 2.9 | 1.1 | 3.0 | 1.3 | 2.8 |
| IV | 0.5 | 1.3 | 0.5 | 1.6 | 0.4 | 0.4 |
| Region | ||||||
| North America | 47.4 | 57.0 | 47.4 | 56.9 | 47.5 | 57.5 |
| Western Europe | 35.5 | 28.3 | 34.8 | 27.9 | 37.0 | 29.4 |
| Eastern Europe | 3.7 | 2.7 | 2.1 | 1.4 | 7.4 | 6.6 |
| Latin America | 1.2 | 0.4 | 1.7 | 0.6 | 0.0 | 0.0 |
| Australia | 6.9 | 8.0 | 7.2 | 8.7 | 6.4 | 6.1 |
| Other | 5.3 | 3.5 | 6.8 | 4.5 | 1.7 | 0.5 |
| Weight (kg), median (25th, 75th) | 78.0 (69.0, 88.0) | 77.0 (68.0, 86.9) | 78.0 (70.0, 88.0) | 77.0 (68.0, 86.0) | 78.0 (68.0, 88.7)¶ | 77.3 (68.0, 88.0)¶ |
| Height (cm), median (25th, 75th) | 170.0 (164.0, 177.0)‡ | 170.1 (163.0, 177.3)‡ | 171.0 (165.0, 177.3)** | 170.1 (164.0, 177.5)** | 170.0 (162.6, 176.0)†† | 170.0 (163.0, 177.0)†† |
| BP (mm Hg), median (25th, 75th) | ||||||
| Systolic | 130.0 (117.0, 150.0) | 130.0 (112.0, 146.0) | 130.0 (115.0, 149.0) | 128.0 (110.0, 145.0) | 133.0 (120.0, 150.0)‡‡ | 132.0 (120.0, 150.0)‡‡ |
| Diastolic | 80.0 (70.0, 90.0) | 77.0 (66.0, 86.0) | 80.0 (70.0, 90.0) | 78.0 (66.0, 88.0) | 78.0 (68.0, 85.0) | 75.0 (65.0, 84.0) |
| Heart rate (bpm), median (25th, 75th) | 72.0 (62.0, 84.0) | 75.0 (63.0, 90.0) | 73.0 (62.0, 85.0) | 75.0 (63.0, 90.0) | 72.0 (63.0, 82.0) | 75.0 (65.0, 88.0) |
| Prior CABG | 6.9§ | 6.0§ | 4.0§§ | 4.4§§ | 13.4 | 10.9 |
| Prior hypertension | 43.6 | 50.5 | 37.9 | 45.7 | 56.4 | 64.4 |
| Prior CHF | 4.1 | 7.6 | 1.9 | 4.9 | 9.1 | 15.7 |
| Prior diabetes mellitus | 17.6 | 20.6 | 15.2 | 18.3 | 23.0 | 27.4 |
| Prior PCI | 7.7 | 6.5 | 4.8¶¶ | 4.4¶¶ | 14.5*** | 12.3*** |
| Prior MI | 20.6 | 24.2 | 16.1 | 20.8 | 30.7§ | 33.8§ |
| US patient | 38.5 | 47.7 | 39.1 | 48.7 | 37.0 | 44.8 |
| Prior CVA, stroke, or TIA | 3.4 | 5.4 | 2.0 | 3.8 | 5.7 | 8.9 |
Data are presented as percentages unless otherwise indicated.
*Significant differences existed between no AF and AF in all groups of patients except where indicated. Significance was defined as p<0.001 owing to sample size. †p = 0.975; ‡p = 0.889; §p = 0.002; ¶p = 0.357; **p = 0.033; ††p = 0.008; ‡‡p = 0.080; §§p = 0.181; ¶¶p = 0.248; ***p = 0.004.
AF, atrial fibrillation. BP, blood pressure; CABG, coronary artery bypass grafting; CHF, congestive heart failure; CVA, cerebrovascular accident; MI, myocardial infarction; NSTE-ACS, non-ST-segment elevation acute coronary syndrome; PCI, percutaneous coronary intervention; STEMI, ST-segment elevation myocardial infarction; TIA, transient ischaemic attack.