| All patients (n = 105) | Score 2 (n = 29) | Score 3 (n = 38) | Score 4 (n = 38) | p Wilcoxon | |
| Age (years) | 70 (2) | 67 (2) | 71 (2) | 70 (2) | 0.28 |
| Gender (male) | 68% | 54% | 65% | 82% | 0.05 |
| Diabetes | 23% | 18% | 24% | 26% | 0.71 |
| Hypertension | 61% | 43% | 76% | 61% | 0.03 |
| CAD | 56% | 54% | 65% | 50% | 0.40 |
| BMI | 28.3 (0.6) | 28.1 (1.2) | 27.6 (1.1) | 29.1 (1.1) | 0.84 |
| Waist circumference (cm) | 100.6 (1.6) | 100.8 (3.1) | 102.2 (2.6) | 98.7 (2.8) | 0.72 |
| Statins | 69% | 58% | 85% | 66% | 0.12 |
| ACE inhibitors | 30% | 25% | 38% | 27% | 0.60 |
| Bicuspid valves | 26% | 19% | 20% | 36% | 0.15 |
| Smoking | 3.8% | 0% | 2.6% | 7.9% | 0.22 |
| Aortic peak gradient (mm Hg) | 71.6 (2.1) | 64.5 (3.5) | 65.3 (3.2) | 83.2 (3.1) | <0.001 |
| Aortic mean gradient (mm Hg) | 42.6 (1.35) | 39.1 (2.3) | 37.6 (2.1) | 50.1 (2.0) | <0.001 |
| Aortic valve area (cm2) | 0.77 (0.02) | 0.79 (0.03) | 0.83 (0.03) | 0.70 (0.03) | 0.04 |
| Creatinine (μmol/l) | 92.8 (2.2) | 87.3 (4.2) | 96.4 (3.7) | 93.6 (3.7) | 0.34 |
| Glycaemia (mmol/l) | 5.6 (0.1) | 5.4 (0.2) | 5.6 (0.2) | 5.6 (0.2) | 0.75 |
| LDL-C (mmol/l) | 2.35 (0.09) | 2.45 (0.18) | 2.15 (0.15) | 2.48 (0.15) | 0.45 |
| HDL-C (mmol/l) | 1.32 (0.03) | 1.41 (0.06) | 1.26 (0.06) | 1.32 (0.06) | 0.03 |
| Triglyceride (mmol/l) | 1.36 (0.06) | 1.28 (0.12) | 1.25 (0.11) | 1.55 (0.10) | 0.20 |
| ApoB (g/l) | 0.70 (0.02) | 0.67 (0.05) | 0.65 (0.04) | 0.77 (0.04) | 0.07 |
| ApoA-I (g/l) | 1.12 (0.02) | 1.11 (0.04) | 1.11 (0.03) | 1.13 (0.03) | 0.95 |
| LDL peak size (Å) | 259.3 (0.6) | 259.5 (1.2) | 259.3 (1.0) | 259.1 (1.0) | 0.96 |
| HDL peak size (Å) | 84.9 (0.6) | 84.8 (1.1) | 86.4 (1.0) | 83.5 (1.0) | 0.11 |
| %LDL <255Å | 37.1 (2.1) | 33.1 (4.0) | 39.9 (3.4) | 38.5 (3.4) | 0.41 |
| LDL-C <255Å (mmol/l) | 0.82 (0.05) | 0.79 (0.10) | 0.84 (0.08) | 0.85 (0.08) | 0.89 |
| CRP (mg/l) | 2.21 (0.25) | 2.41 (0.47) | 2.47 (0.42) | 1.80 (0.42) | 0.48 |
| Circulating ox-LDL (U/l) | 32.9 (1.5) | 27.3 (2.6) | 32.2 (2.3) | 38.3 (2.3) | 0.02 |
Results expressed as mean (SEM) unless otherwise stated.
ACE, angiotensin converting enzyme; Apo, apolipoprotein; BMI, body mass index; CAD, coronary artery disease; CRP, c-reactive protein; HDL, high-density lipoprotein; LDL, low-density lipoprotein; ox-LDL, oxidized low-density lipoprotein.