| Pulmonary arterial hypertension | Disease-targeted therapies (but caution in veno-occlusive disease) |
| PH with left heart disease | Medical, interventional and surgical therapies for chronic heart failure, coronary artery disease, valve disease and pericardial disease |
| PH associated with lung diseases and/or hypoxaemia | Therapy to treat the primary lung disorder |
| Oxygen |
| Disease-targeted therapies when pulmonary hypertension out of proportion to lung disease |
| PH due to chronic thrombotic and/or embolic disease | Pulmonary endarterectomy (PEA) for proximal disease |
| Disease-targeted therapies for distal disease (see section 6.4.8.7), significant residual post-PEA pulmonary hypertension or late redevelopment of symptomatic pulmonary hypertension post-PEA |
| Miscellaneous | Specific to individual diseases |