Table 1 Clinical characteristics of study cohort and univariable relationship to 30-day mortality
CharacteristicAll patients (n = 1994)30-day mortality
Alive (n = 1944)Died (n = 50)Odds ratio (95% CI)p Value
Age (years)66 (59 to 72)66 (59 to 72)72 (64 to 76)1.06 (1.02 to 1.10)*0.001
Risk factors and medical history
    Male1548 (78%)1513 (78%)35 (70%)0.67 (0.36 to 1.23)0.19
    Current smoker204 (10%)202 (10%)2 (4%)0.36 (0.09 to 1.49)0.16
    Diabetes304 (15%)295 (15%)9 (18%)1.23 (0.59 to 2.55)0.59
    Hypertension1199 (60%)1170 (60%)29 (58%)0.91 (0.52 to 1.61)0.75
    Prior percutaneous coronary intervention163 (8%)160 (8%)3 (6%)0.71 (0.22 to 2.31)0.57
    Prior cardiac surgery42 (2%)39 (2%)3 (6%)3.12 (0.93 to 10.45)0.07
    Previous myocardial infarction978 (49%)954 (49%)24 (48%)0.96 (0.55 to 1.68)0.88
    Left ventricular ejection fraction <50%†677 (34.2%)652 (33.8%)25 (50%)1.96 (1.12 to 3.44)0.02
    BMI†28.0 (4.1)28.0 (4.1)26.9 (4.4)0.93 (0.86 to 1.00)0.06
New York Heart Association functional class†
    I or II875 (47%)858 (47%)17 (39%)
    III or IV985 (53%)958 (53%)27 (61%)1.42 (0.77 to 2.63)0.26
Estimated glomerular filtration rate (ml/min/1.73 m2)64 (14)64 (14)54 (15)0.64 (0.53 to 0.76)‡<0.001
EuroSCORE†4 (2 to 6)4 (2 to 6)7 (5 to 8)1.39 (1.27 to 1.52)<0.001
Carstairs score−2.28 (−3.70 to −0.20)−2.28 (−3.70 to −0.26)−1.14 (−2.87 to +0.50)1.09 (1.00 to 1.20)0.06
Operative data
    Preoperative intra-aortic balloon pump75 (4%)70 (4%)5 (10%)2.97 (1.14 to 7.71)0.03
    Additional major operative procedure§219 (11%)201 (10%)18 (36%)4.88 (2.69 to 8.85)<0.001
    Time on bypass (min)79 (59 to 97)78 (59 to 96)109 (84 to 175)1.17 (1.13 to 1.22)¶<0.001
    Cross clamp time (min)43 (32 to 54)43 (32 to 53)53 (45 to 102)1.19 (1.12 to 1.25)¶<0.001
  • Categorical data are expressed as number (percentage) and continuous data as mean (standard deviation) if normally distributed (BMI and estimated GFR) or median (interquartile range) if skewed (other continuous variables).

  • *Odds ratio per year.

  • †Left ventricular ejection fraction was not defined in 13 cases, BMI was not accurately recorded in 40 patients, New York Heart Association functional class was not recorded in 134 patients, and EuroSCORE was not accurately recorded in 14 patients. Percentages refer to patients with data available.

  • ‡Odds ratio per 10 ml/min/1.73 m2.

  • §See text for details.

  • ¶Odds ratio per 10 min.