Control N = 82 | SLE N = 82 | p Value | |
Clinical parameters | |||
Age (year) | 49 (13) | 45 (9) | 0.060 |
Body mass index (kg/m2) | 22.7 (3.4) | 22.4 (3.6) | 0.592 |
Body surface area (m2) | 1.54 (0.09) | 1.52 (0.14) | 0.596 |
Systolic BP (mm Hg) | 126 (10) | 126 (18) | 0.983 |
Diastolic BP (mm Hg) | 76 (7) | 77 (11) | 0.524 |
Mean arterial pressure (mm Hg) | 92 (8) | 93 (12) | 0.707 |
HR (bpm) | 67 (10) | 68 (12) | 0.463 |
LV parameters | |||
LV end-diastolic volume (cm3) | 75.9 (10.6) | 73.4 (19.0) | 0.285 |
LV end-systolic volume (cm3) | 24.6 (4.7) | 24.3 (8.9) | 0.774 |
LV ejection fraction (%) | 69.1 (7.1) | 67.1 (6.8) | 0.078 |
LV stroke volume (ml) | 51.3 (8.2) | 49.1 (13.4) | 0.196 |
Cardiac index (l/min·m2) | 2.26 (0.3) | 2.18 (0.64) | 0.234 |
Interventricular septum thickness (cm) | 0.86 (0.15) | 0.96 (0.17) | <0.001 |
Posterior wall thickness (cm) | 0.81 (0.13) | 0.92 (0.14) | <0.001 |
LV mass index (g/m2) | 80.1 (10.7) | 90.2 (24.5) | 0.001 |
RV parameters | |||
LV to RV dimension ratio | 1.52 (0.17) | 1.44 (0.27) | 0.018 |
RV fractional area change (%) | 46.3 (6.6) | 46.1 (11.7) | 0.855 |
PASP (mm Hg) | 13.4 (9.4) | 33.6 (16.1) | <0.001 |
RV free wall thickness (cm) | 0.39 (0.06) | 0.44 (0.09) | <0.001 |
LV parameters by tissue Doppler imaging | |||
Sm of six basal segments (cm/s) | 6.06 (1.01) | 5.02 (1.05) | <0.001 |
Sm of 12 segments (cm/s) | 4.97 (1.01) | 4.18 (0.89) | <0.001 |
S′ at mitral septum annulus | 8.06 (0.92) | 7.80 (1.54) | 0.193 |
S′ at mitral lateral annulus | 10.05 (1.66) | 9.28 (2.20) | 0.012 |
Em of six basal segments (cm/s) | 7.71 (1.92) | 7.06 (2.10) | 0.039 |
Em of 12 basal segments (cm/s) | 6.49 (1.72) | 5.91 (1.78) | 0.036 |
RV parameters by tissue Doppler imaging | |||
S′ at tricuspid lateral annulus | 13.79 (1.03) | 12.15 (2.38) | 0.026 |
S′ at tricuspid lateral annulus <11.5 cm/s | 0 | 34 (41.5%) | <0.001 |
Sm of basal and mid RV free wall (cm/s) | 8.00 (1.39) | 6.88 (1.67) | <0.001 |
Complex echocardiographic parameters | |||
MWFS | 0.19 (0.02) | 0.17 (0.03) | <0.001 |
MWFS <0.15 | 0 | 20 (24.4%) | <0.001 |
Stress-corrected MWFS (MWFS/cESS) (cm2/kdyne·10−2) | 0.22 (0.04) | 0.20 (0.05) | 0.039 |
FS/mESS | 0.71 (0.17) | 0.68 (0.22) | 0.381 |
Vascular parameters | |||
Systemic vascular resistance index, SVRI (dyne·s·cm−5·m2) | 3487 (463) | 3803 (1253) | 0.035 |
Total arterial compliance (ml/mm Hg) | 1.09 (0.17) | 1.04 (0.34) | 0.231 |
cESS, left ventricular circumferential end-systolic wall stress; LV, left ventricular; MWFS, midwall fractional shortening; PASP, pulmonary artery systolic pressure; RV, right ventricular; S′, pulsed wave peak systolic velocity at annulus; Sm, mean myocardial systolic peak velocity.