Table 1 Clinical data for patients who did and did not develop late significant tricuspid regurgitation (TR) after left-sided valve surgery
Late significantLate significantp Value
TR (−) (n = 589)TR (+) (n = 49)
Age, years50 (14)55 (14)0.018
Female gender, n245 (42%)37 (76%)<0.001
Atrial fibrillation, n206 (35%)33 (67%)<0.001
Rheumatic aetiology, n249 (42%)36 (74%)<0.001
Underlying valvular lesion0.006
    Mitral, n292 (50%)31 (63%)
    Aortic, n214 (36%)7 (14%)
    Both, n83 (14%)11 (22%)
Surgical procedures
    CABG, n27 (5%)4 (8%)0.287
    Maze, n50 (9%)3 (6%)0.788
    CPB time, min122 (56)125 (57)0.740
    Aortic clamp time, min83 (42)83 (40)0.913
Preoperative data
    Left atrial AP diameter, mm52 (11)57 (14)0.001
    RV dimension, mm18 (4)17 (4)0.924
    Left ventricular EF, %57 (10)58 (8)0.597
    TR grade0.8 (0.7)1.0 (0.6)0.007
    TV annulus diameter, mm31 (5)32 (6)0.723
    Peak PG of TR, mm Hg30 (12)30 (10)0.909
Immediate echocardiographic changes (Δ; post–preoperative)
    ΔLVIDs, mm−2 (6)−4 (7)0.031
    ΔLVIDd, mm−8 (8)−9 (8)0.615
    ΔLV EF, %−7 (12)−5 (11)0.429
    ΔRV dimension, mm−2 (3)−1 (3)0.782
Late follow-up data
    Atrial fibrillation, n169 (28%)33 (67%)<0.001
    Left atrial AP diameter, mm45 (8)53 (12)<0.001
    Left ventricular EF, %58 (9)58 (8)0.671
    TV annulus diameter, mm35 (5)40 (7)<0.001
    Peak PG of TR, mm Hg24 (6)31 (11)<0.001
Left-sided valvular dysfunction
    Prosthesis malfunction, n27 (5%)7 (14%)0.011
    New valvular lesion, n3 (1%)2 (4%)0.050
  • Continuous variables are expressed as mean (SD).

  • AP, anterior–posterior; CABG, coronary artery bypass graft; CPB, cardiopulmonary bypass; EF, ejection fraction; LVIDd, left ventricular diastolic dimension; LVIDs, left ventricular systolic dimension; PG, pressure gradient; RV, right ventricle; TV, tricuspid valve.