Table 1 Main advantages and disadvantages of the most commonly used platelet assays
Platelet assaysAdvantagesDisadvantages
AggregometryGold standardVariable reproducibility, time consuming, requires an experienced operator, sample preparation, not standardised, not specific for the P2Y12 ADP receptor. Influenced by aspirin and glycoprotein IIb/IIIa inhibitors
VerifyNow P2Y12Small blood volume, whole-blood assay, rapid, bedsideInfluenced by glycoprotein IIb/IIIa
VASPSmall blood volume, whole-blood assay, specific for the P2Y12 ADP receptorSample preparation, requires flow-cytometer, experienced operator
  • ADP, adenosine diphosphate; VASP, vasodilator-stimulated phosphoprotein.