Table 2 Main studies investigating the relationship between biological clopidogrel resistance and thrombotic events after percutaneous coronary intervention

End point	Study	Platelet assays used	n
Stent thrombosis	Barragan et al16	VASP-P index	36
	Gurbel et al17	VASP-P index, ADP-induced aggregometry	120
	Buonamici et al18	ADP-induced aggregometry	804
	Blindt et al19	VASP-P index, ADP-induced aggregometry	99

Ischaemic events
CV death, MI, unstable angina, stroke	Gurbel et al21	ADP-induced aggregometry	192
Death, MI, stent thrombosis, stroke, ischaemia	Bliden et al22	ADP-induced aggregometry	100
CV death, acute or subacute stent thrombosis, ACS, ischaemic stroke	Frere et al24	ADP-induced aggregometry, VASP-P index	195
CV death, MI, urgent TVR	Bonello et al23	VASP-P index	144
CV death, acute and subacute stent thrombosis, MI	Price et al20	VerifyNow P2Y₁₂	380

ACS, acute coronary syndromes; ADP, adenosine diphosphate; CV, cardiovascular; MI, myocardial infarction; TVR, target vessel revascularisation; VASP, vasodilator-stimulated phosphoprotein.