Study | Year | Patients | Stent type | Antiplatelet therapy | Perioperative therapy | Outcome |
Kaluza et al6 | 2000 | 40 | BMS | Aspirin + ticlopidine | Most discontinued both agents | 20% Mortality within 4 weeks of stenting |
Wilson et al7 | 2003 | 207 | BMS | Aspirin + warfarin or ticlopidine or clopidogrel | 26% Continued dual therapy | 4.8% MI/stent thrombosis within 6 weeks, none after 6 weeks |
Reddy/Vaitkus8 | 2005 | 56 | BMS | Aspirin + clopidogrel | 60% had MACE on clopidogrel at surgery | 14% MACE within 6 weeks of stenting, none after 6 weeks |
Sharma et al9 | 2004 | 47 | BMS | Aspirin + ticlopidine or clopidogrel | 25% Stopped thienopyridine within 3 weeks of stenting | 85% Mortality within 3 weeks if antiplatelet agents stopped, few events beyond 3 weeks |
Compton et al13 | 2006 | 38 | DES | Aspirin + clopidogrel | 41% Receiving clopidogrel at time of surgery | 0% Event rate, relatively late surgery (median 260 days) |
Kim et al14 | 2007 | 239 | BMS/DES | Aspirin + clopidogrel | Stopped 5–7 days before elective surgery | 2.2% MACE DES group, 0% BMS group |
BMS, bare metal stent; DES, drug-eluting stent; MACE, major adverse cardiac event; MI, myocardial infarction.