Independent variable | Odds ratio (95% CI)* | p Value |
BNP >160 ng/l | 9.9 (4.3 to 22.8) | <0.001 |
MR-proANP >147 pmol/l | 6.4 (2.3 to 17.5) | <0.001 |
MR-proADM >0.52 nmol/l | 1.4 (0.4 to 4.4) | 0.582 |
Adiponectin >8.7 mg/l | 1.9 (0.7 to 5.2) | 0.183 |
CT-proET-1 >28 pmol/l | 1.1 (0.3 to 3.5) | 0.904 |
Proguanylin >6.0 ng/ml | 1.0 (0.3 to 3.3) | 0.988 |
sST2 >121 ng/l | 1.1 (0.4 to 3.2) | 0.887 |
Prouroguanylin >4.0 ng/ml | 0.7 (0.2 to 2.7) | 0.568 |
Copeptin >5.2 pmol/l | 1.1 (0.3 to 3.4) | 0.891 |
Chromogranin A >3.4 nmol/l | 0.9 (0.2 to 3.6) | 0.907 |
Observed frequencies: patients with dyspnoea caused by acute destabilised HF, nā=ā137; patients with dyspnoea attributable to other causes, nā=ā114.
*Multivariate odds ratios were calculated with logistic regression analysis without variable selection technique (all independent variables were included simultaneously into the model). Biomarkers were dichotomised according to the given cut-off value which represents the 90% sensitivity criterion.