Table 2 Comparison of reverse remodelling and changes in other echocardiographic and clinical parameters at three months after cardiac resynchronisation therapy between ischaemic and non-ischaemic patients

Parameters	All patients (n = 119)		Ischaemic (n = 52)		Non-ischaemic (n = 67)		Ischaemic vs non-ischaemic
Parameters		p Value		p Value		p Value	p Value
ΔLVEDV (cm³)	−21 (31)	<0.001	−17 (27)	<0.001	−25 (33)	<0.001	0.169
ΔLVESV (cm³)	−26 (30)	<0.001	−21 (26)	<0.001	−31 (33)	<0.001	0.082
ΔLV ejection fraction (%)	7.4 (6.9)	<0.001	5.9 (6.0)	<0.001	8.6 (7.4)	<0.001	0.032
ΔSphericity index, end-diastole	0.09 (0.23)	<0.001	0.06 (0.22)	0.060	0.11 (0.23)	0.001	0.288
ΔSphericity index, end-systole	0.13 (0.29)	<0.001	0.10 (0.28)	0.018	0.16 (0.31)	<0.001	0.294
ΔMitral regurgitation (%)	−10 (17)	<0.001	−8 (16)	0.003	−12 (17)	<0.001	0.219
ΔMPI	−0.15 (0.26)	<0.001	−0.12 (0.29)	0.016	−0.16 (0.24)	<0.001	0.348
ΔLV filling time (ms)	59 (147)	<0.001	38 (125)	0.057	76 (161)	0.001	0.204
ΔQuality of life score	−9 (22)	<0.001	−7 (18)	0.015	−11 (24)	<0.001	0.267
Δ6-minute hall-walk distance (metres)	32 (81)	<0.001	22 (93)	0.141	40 (70)	<0.001	0.256
ΔNYHA class, % of patients
Improvement of two classes	10		8		12
Improvement of one class	63	<0.001	56	<0.001	67	<0.001	0.092
No improvement	24		34		18
Deterioration of one class	3		2		3

Δ, changes between three-month follow-up and baseline; LV, left ventricular; LVEDV, left ventricular end-diastolic volume; LVESV, left ventricular end-systolic volume; MPI: myocardial performance index; NYHA, New York Heart Association.